Determination of ochratoxin A in beer by LC-MS/MS ion trap detection

被引：51
|
作者：
Reinsch, M. [1 ]
Toepfer, A. [1 ]
Lehmann, A. [1 ]
Nehls, I. [1 ]
Panne, U. [1 ]
机构：
[1] Fed Inst Mat Res & Testing, Dept Analyt Chem Ref Mat, D-12489 Berlin, Germany
来源：
FOOD CHEMISTRY | 2007年 / 100卷 / 01期
关键词：
ochratoxin A; beer; tandem mass spectrometry; solid phase/anion exchange extraction; liquid chromatography;
D O I：
10.1016/j.foodchem.2005.10.005
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Ochratoxin A (OTA) is a mycotoxin produced by Aspergillus ochraceus and Penicillium verrucosum. It was analysed in food and beverages so far. Due to its toxicity, the European community issued directives and some countries own regulations for OTA contents in food, feed, and beverages. This work describes a method for the determination of OTA in beer. It is based on a combined anion exchange/reversed phase clean-up and liquid chromatography with tandem mass spectrometry. This method was compared with a modified standard method and validated on the basis of spiked beer samples. The accuracy was checked with statistical tools (t-test). Due to its good reproducibility, repeatability and robustness this method is a promising alternative to LC-FD (fluorescence detection) techniques. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码：312 / 317
页数：6
相关论文
共 50 条
  • [1] DETERMINATION OF OCHRATOXIN A IN FOOD BY LC-MS/MS
    Vartolomei, Anca
    Vlase, Laurian
    Cuciureanu, Magdalena
    Cuciureanu, Rodica
    Popa, Daniel Saveta
    [J]. FARMACIA, 2014, 62 (02) : 287 - 298
  • [2] Comparison of Flow Injection-MS/MS and LC-MS/MS for the Determination of Ochratoxin A
    Zhang, Kai
    [J]. TOXINS, 2021, 13 (08)
  • [3] LC-MS/MS Determination of Mono-Glutamate Folates and Folic Acid in Beer
    Terenzio Bertuzzi
    Silvia Rastelli
    Annalisa Mulazzi
    Filippo Rossi
    [J]. Food Analytical Methods, 2019, 12 : 722 - 728
  • [4] Development and validation of LC-MS/MS method for the determination of Ochratoxin A and its metabolite Ochratoxin in poultry tissues and eggs
    Paoloni, Angela
    Solfrizzo, Michele
    Bibi, Rita
    Pecorelli, Ivan
    [J]. JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES, 2018, 53 (05) : 327 - 333
  • [5] LC-MS/MS Determination of Mono-Glutamate Folates and Folic Acid in Beer
    Bertuzzi, Terenzio
    Rastelli, Silvia
    Mulazzi, Annalisa
    Rossi, Filippo
    [J]. FOOD ANALYTICAL METHODS, 2019, 12 (03) : 722 - 728
  • [6] Determination of penicillins in milk using LC-UV, LC-MS and LC-MS/MS
    Martinez-Huelamo, Miriam
    Jimenez-Gamez, Esther
    Pilar Hermo, Maria
    Barron, Dolores
    Barbosa, Jose
    [J]. JOURNAL OF SEPARATION SCIENCE, 2009, 32 (14) : 2385 - 2393
  • [7] Determination of vitamin D metabolites in serum using LC-MS and LC-MS/MS
    Bedner, Mary
    Phinney, Karen W.
    Sander, Lane C.
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009, 237 : 301 - 301
  • [8] Detection of doping agents by LC-MS and LC-MS-MS
    Deventer, K.
    Pozo, O. J.
    Van Eenoo, P.
    Delbeke, F. T.
    [J]. LC GC NORTH AMERICA, 2008, 26 (04) : 376 - +
  • [9] Simultaneous Quantification of Aflatoxins, Ochratoxin A and Zearalenone in Cereals by LC-MS/MS
    Liao, Chia-Ding
    Lin, Hsu-Yang
    Chiueh, Lih-Ching
    Shih, Daniel Yang-Chih
    [J]. JOURNAL OF FOOD AND DRUG ANALYSIS, 2011, 19 (03) : 259 - 268
  • [10] LC-MS/MS determination of Synercid® injections
    Abdel-Hamid, ME
    Phillips, OA
    [J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2003, 32 (06) : 1167 - 1174
12345