Synthesis and biological activity of a retinyl phosphonic acid derivative an analog of retinyl phosphate: Homoretinylphosphonic acid

被引：0
|
作者：
Kamal, M [1 ]
Winum, JY [1 ]
Barragan, V [1 ]
Leydet, A [1 ]
Montero, JL [1 ]
机构：
[1] Univ Montpellier 2, CNRS, Lab Chim Biomol, F-34095 Montpellier 05, France
来源：
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 1999年 / 152卷
关键词：
homoretinylphosphonic acid; phosphonate; retinylphosphate; glycoconjugate;
D O I：
10.1080/10426509908031633
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
The synthesis of phosphonate isosteres or homologues of natural retinylphosphate was developed starting from carbonylated terpenes, through Abramov and Wittig-Horner reactions, Homoretinylphosphonic acid (HRP) was isolated and tested for its ability to be involved in the biosynthesis of membrane glycoconjugates.
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收藏
页码：241 / 256
页数：16
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