Treatment landscape of metastatic prostate cancer: the role of radium-223

被引：0
|
作者：
Dermine, Alexandre
Machiels, Jean-Pascal
机构：
[1] Catholic Univ Louvain, Dept Med Oncol, Inst Roi Albert 2, Clin Univ St Luc, Brussels, Belgium
[2] Catholic Univ Louvain, Inst Rech Clin & Expt Pole MIRO, Brussels, Belgium
来源：
ACTA CLINICA BELGICA | 2017年 / 72卷 / 01期
关键词：
Metastatic castrate-resistant prostate cancer; Radiopharmaceutical; Radium-223; BONE METASTASES; SKELETAL METASTASES; ZOLEDRONIC ACID; DOUBLE-BLIND; ABIRATERONE ACETATE; SURVIVAL ANALYSIS; EMITTING RA-223; PLUS PREDNISONE; OPEN-LABEL; PHASE-II;
D O I：
10.1080/17843286.2016.1203545
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The landscape of metastatic prostate cancer has changed recently with the availability of six new molecules showing an overall survival benefit. The development of compounds able to decrease the rate of complications from bone metastasis has also led to improvements in overall morbidity associated with this disease. In this paper, we briefly review the currently available drugs indicated in the treatment of metastatic prostate cancer, focusing on the place of the radiopharmaceutical agent radium-223 and its very unique mechanism of action and safety profile.
引用
收藏
页码：19 / 23
页数：5
相关论文
共 50 条
  • [1] Radium-223 in the treatment of metastatic prostate cancer
    Marques, I. A.
    Abrantes, A. M.
    Pires, A. S.
    Costa, G.
    Tavares-Silva, E.
    Botelho, M. F.
    EUROPEAN JOURNAL OF CANCER, 2016, 61 : S47 - S47
  • [2] Radium-223 dichloride for the treatment of metastatic prostate cancer
    Turner, Philip Geoffrey
    O'Sullivan, Joe
    EXPERT OPINION ON PHARMACOTHERAPY, 2014, 15 (14) : 2105 - 2111
  • [3] Radium-223 for the treatment of prostate cancer
    Hafeez, Shaista
    Parker, Christopher
    EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2013, 22 (03) : 379 - 387
  • [4] The role of radium-223 in the evolving treatment landscape of metastatic castration-resistant prostate cancer: A narrative review
    Pinto, Alvaro
    Dominguez, Mario
    Gomez-Iturriaga, Alfonso
    Rodriguez-Vida, Alejo
    Vallejo-Casas, Juan Antonio
    Castro, Elena
    CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 2025, 210
  • [5] Residents' Guide to Radium-223 Dichloride Treatment For Metastatic Prostate Cancer
    Ersahin, Devrim
    Chen, Ming-Kai
    JOURNAL OF NUCLEAR MEDICINE, 2016, 57
  • [6] Radium-223 In The Treatment Of Metastatic Castration-Resistant Prostate Cancer
    Vazzana, C.
    Morano, S.
    Di Lascio, A.
    Grana, C.
    Chinol, M.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2017, 44 : S880 - S880
  • [7] Radium-223 in metastatic castration resistant prostate cancer
    Vuong, Winston
    Sartor, Oliver
    Pal, Sumanta K.
    ASIAN JOURNAL OF ANDROLOGY, 2014, 16 (03) : 348 - 353
  • [8] Utilization of Radium-223 in Metastatic Prostate Cancer Patients and Novel Prognostic Indicators In Radium-223 Patients
    Parsons, M. W.
    Tward, J. D.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2020, 108 (03): : E899 - E899
  • [9] Radium-223 for Metastatic Castrate-Resistant Prostate Cancer
    Sindhu, Kunal K.
    Nehlsen, Anthony D.
    Stock, Richard G.
    PRACTICAL RADIATION ONCOLOGY, 2022, 12 (04) : 312 - 316
  • [10] Immune Analysis of Radium-223 in Patients With Metastatic Prostate Cancer
    Kim, Joseph W.
    Shin, Min Sun
    Kang, Youna
    Kang, Insoo
    Petrylak, Daniel P.
    CLINICAL GENITOURINARY CANCER, 2018, 16 (02) : E469 - E476
12345