Multicentric Analysis of the Species Distribution and Antifungal Susceptibility of Cryptic Isolates from Aspergillus Section Fumigati

被引：19

作者：

Imbert, S. ^{[1
,2
]}

Normand, A. C. ^{[1
]}

Cassaing, S. ^{[3
]}

Gabriel, F. ^{[4
]}

Kristensen, L. ^{[5
]}

Bonnal, C. ^{[6
]}

Lachaud, L. ^{[7
]}

Costa, D. ^{[8
]}

Guitard, J. ^{[9
]}

Hasseine, L. ^{[10
]}

Palous, M. ^{[1
]}

Piarroux, M. ^{[1
,11
]}

Hendrickx, M. ^{[12
]}

Piarroux, R. ^{[1
,11
]}

Fekkar, A. ^{[1
,2
]}

机构：

[1] Grp Hosp La Pitie Salpetriere, AP HP, Serv Parasitol Mycol, Paris, France

[2] Sorbonne Univ, Ctr Immunol & Malad Infect, CNRS, INSERM, Paris, France

[3] CHU Toulouse, Serv Parasitol Mycol, Toulouse, France

[4] CHU Bordeaux, Serv Parasitol Mycol, Bordeaux, France

[5] Aarhus Univ Hosp, Dept Clin Microbiol, Aarhus, Denmark

[6] Hop Bichat Claude Bernard, AP HP, Serv Parasitol Mycol, Paris, France

[7] CHU Montpellier, Serv Parasitol Mycol, Montpellier, France

[8] CHU Rouen, Serv Parasitol Mycol, Rouen, France

[9] Hop St Antoine, AP HP, Serv Parasitol Mycol, Paris, France

[10] CHU Nice, Serv Parasitol Mycol, Nice, France

[11] Sorbonne Univ, INSERM, Inst Pierre Louis Epidemiol & Sante Publ, Paris, France

[12] Sci Inst Publ Hlth, BCCM IHEM Fungal Collect, Serv Mycol & Aerobiol, Brussels, Belgium

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2020年 / 64卷 / 12期

关键词：

Aspergillus section Fumigati; cryptic species; MALDI-TOF mass spectrometry; azole resistance; Aspergillus thermomutatus; Aspergillus lentulus; antifungal susceptibility testing; IDENTIFICATION; RARE; MISIDENTIFICATION; NEOSARTORYA;

D O I：

10.1128/AAC.01374-20

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The antifungal susceptibility of Aspergillus cryptic species is poorly known. We assessed 51 isolates, belonging to seven Fumigati cryptic species, by the EUCAST reference method and the concentration gradient strip (CGS) method. Species-specific patterns were observed, with high MICs for azole drugs, except for Aspergillus hiratsukae and Aspergillus tsurutae, and high MICs for amphotericin B for Aspergillus lentulus and Aspergillus udagawae. Essential and categorical agreements between EUCAST and CGS results were between 53.3 and 93.3%.

引用

页数：6

共 50 条

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