Effectiveness of Using the Modified Checklist for Autism in Toddlers in Two-Stage Screening of Autism Spectrum Disorder at the 18-Month Health Check-Up in Japan

被引：58
|
作者：
Kamio, Yoko [1 ]
Inada, Naoko [1 ]
Koyama, Tomonori [1 ]
Inokuchi, Eiko [1 ]
Tsuchiya, Kenji [2 ]
Kuroda, Miho [1 ]
机构：
[1] Natl Ctr Neurol & Psychiat, Natl Inst Mental Hlth, Dept Child & Adolescent Mental Hlth, Kodaira, Tokyo 1878553, Japan
[2] Hamamatsu Univ, Sch Med, United Grad Sch Child Dev, Res Ctr Child Mental Dev, Hamamatsu, Shizuoka 4312102, Japan
来源：
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS | 2014年 / 44卷 / 01期
关键词：
Autism spectrum disorder; Community-based surveillance; Early detection; Modified Checklist for Autism in Toddlers (M-CHAT); Screening; RATING-SCALE; CHILDREN; IDENTIFICATION; QUESTIONNAIRE; INTERVIEW; VALIDITY; VERSION; RISK; AGE;
D O I：
10.1007/s10803-013-1864-1
中图分类号：
B844 [发展心理学（人类心理学）];
学科分类号：
040202 ;
摘要：
To determine whether the Modified Checklist for Autism in Toddlers (M-CHAT) in conjunction with the routine 18-month health check-up identifies Japanese toddlers with autism spectrum disorder (ASD). Two-stage screening using the M-CHAT was conducted with 1,851 children attending the check-up. Final ASD diagnosis was confirmed at age a parts per thousand yen3 years. Screening identified 20/51 children with ASD: 12/20 true positives were developmentally delayed, whereas 16/22 false negatives were high-functioning. Sensitivity was 0.476, specificity 0.986, positive predictive value 0.455, and likelihood ratio 33.4 for children with ASD. With a few modifications, M-CHAT screening successfully detected toddlers with ASD with and without developmental delay and is a promising screening tool to complement existing community surveillance.
引用
收藏
页码：194 / 203
页数：10
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