Thalidomide in the treatment of refractory rheumatoid arthritis

被引：0
|
作者：
Keesal, N [1 ]
Wasserman, MJ [1 ]
Bookman, A [1 ]
Lapp, V [1 ]
Weber, DA [1 ]
Keystone, EC [1 ]
机构：
[1] Univ Toronto, Mt Sinai Hosp, Dept Med, Ctr Adv Therapeut Arthrit, Toronto, ON M5G 1X5, Canada
来源：
JOURNAL OF RHEUMATOLOGY | 1999年 / 26卷 / 11期
关键词：
thalidomide; rheumatoid arthritis; therapy;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Objective. To review outcomes in 10 patients with rheumatoid arthritis (RA) treated with thalidomide. Methods. We reviewed our experience with 10 patients treated with thalidomide using a standard therapeutic protocol and standard outcome measures. Results. We observed no significant improvement in any outcome measure, likely as a consequence of the limited duration of therapy related to thalidomide toxicity. Conclusion. Formal studies of the efficacy of thalidomide in RA are required with alternative doses of the compound used by us, or with compounds derived From other sources.
引用
收藏
页码：2344 / 2347
页数：4
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