Fusobacterium spp. and colorectal cancer: cause or consequence?

被引:49
|
作者
Keku, Temitope O. [1 ,2 ]
McCoy, Amber N. [1 ]
Azcarate-Peril, Andrea M. [1 ,3 ,4 ]
机构
[1] Univ N Carolina, Ctr Gastrointestinal Biol & Dis, Chapel Hill, NC 27599 USA
[2] Univ N Carolina, Dept Med, Div Gastroenterol & Hepatol, Chapel Hill, NC USA
[3] Univ N Carolina, Ctr Gastrointestinal Biol & Dis, Microbiome Core Facil, Chapel Hill, NC USA
[4] Univ N Carolina, Dept Cell & Mol Physiol, Chapel Hill, NC USA
关键词
D O I
10.1016/j.tim.2013.08.004
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Although increasing evidence suggests a relationship between bacterial dysbiosis and colorectal cancer (CRC), few studies have identified specific microbial etiologic factors. Recent studies have implicated overabundance of Fusobacterium in association with colorectal adenomas and cancer. Two articles published in Cell Host & Microbe provide insights into the Fusobacterium-CRC relationship.
引用
收藏
页码:506 / 508
页数:3
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