Leptin is a link between adipose tissue and inflammation

被引：42
|
作者：
Haerle, Peter [1 ]
Straub, Rainer H. [1 ]
机构：
[1] Univ Hosp Regensburg, Lab Expt Rheumatol & Neuroendocrinoimmunol, Div Rheumatol, Dept Internal Med 1, D-93042 Regensburg, Germany
来源：
BASIC AND CLINICAL ASPECTS OF NEUROENDOCRINE IMMUNOLOGY IN RHEUMATIC DISEASES | 2006年 / 1069卷
关键词：
leptin; immune system; neuroendocrine system;
D O I：
10.1196/annals.1351.044
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Leptin is a hormone of the pluripotent white adipose tissue and confers a multitude of regulatory functions within the organism. It controls the energy storage, lipoprotein metabolism, acute phase reactants, sex hormones and glucocorticoid metabolism, and immune function. In this review, we describe these multiple functions of leptin, the regulation of leptin expression, and how leptin can modulate the immune system via direct and indirect mechanisms. We show how leptin can be a link between the adipose tissue and inflammation.
引用
收藏
页码：454 / 462
页数：9
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