"Terpenoids with activity in the Central Nervous System (CNS)".

被引:34
|
作者
Passos, Carolina S. [1 ]
Arbo, Marcelo D. [1 ]
Rates, Stela. M. K. [1 ]
von Poser, Gilsane L. [1 ]
机构
[1] Univ Fed Rio Grande do Sul, Fac Farm, Programa Posgrad Ciencias Farmaceut, BR-90610000 Porto Alegre, RS, Brazil
关键词
Terpenoids; central nervous system; neurotransmitters; ESSENTIAL OIL; SALVINORIN-A; GINSENOSIDES RB1; ALPHA-THUJONE; EXTRACT; PLANTS; GLUTAMATE; CANNABIDIOL; HIPPOCAMPAL; CONSTITUENTS;
D O I
10.1590/S0102-695X2009000100024
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
"Terpenoids with activity in the Central Nervous System (CNS)". The terpenoids are a large group of secondary metabolites which display many activities in the CNS, such as sedative; ansiolytic, antinociceptive, anticonvulsant, pro-convulsant,and hallucinogenic. In this work, we performed a research on terpenoids that exert effects on the CNS, focusing molecules and neurotransmitter systems. related to their actions. The substances approached were classified as mono, sesqui, di, tri and meroterpenoids and include isolated compounds and plants which exert activities mainly on GABAergic, glutamatergic, dopaminergic and opioid neurotransmitter systems.
引用
收藏
页码:140 / 149
页数:10
相关论文
共 50 条
  • [1] Terpenoids and Aromatic Compounds from Bryophytes and their Central Nervous System Activity
    Ludwiczuk, Agnicszka
    Asakawa, Yoshinori
    [J]. CURRENT ORGANIC CHEMISTRY, 2020, 24 (01) : 113 - 128
  • [2] Database mining applied to central nervous system (CNS) activity
    Pintore, M
    Taboureau, O
    Ros, F
    Chrétien, JR
    [J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2001, 36 (04) : 349 - 359
  • [3] Central Nervous System (CNS) Thrombosis
    Th Mantziou
    H Platokouki
    B Karabelas
    Z Kapsimali
    E Adamtziki
    A Covanis
    A Skardoutsou
    A Constantopoulos
    S Aronis
    [J]. Pediatric Research, 1999, 45 : 766 - 766
  • [4] CATALASE ACTIVITY OF CENTRAL-NERVOUS-SYSTEM (CNS) IN ALCOHOLIC GENERATIONAL RATS
    EGANA, E
    MORALES, M
    [J]. JOURNAL OF NEUROCHEMISTRY, 1995, 65 : S198 - S198
  • [5] Central nervous system (CNS) thrombosis.
    Mantziou, T
    Platokouki, H
    Karabelas, B
    Kapsimali, Z
    Adamtziki, E
    Covanis, A
    Skardoutsou, A
    Constantopoulos, A
    Aronis, S
    [J]. PEDIATRIC RESEARCH, 1999, 45 (05) : 766 - 766
  • [6] MRI of central nervous system (CNS) vasculitis
    Abe, Kazuo
    [J]. CURRENT MEDICAL IMAGING REVIEWS, 2006, 2 (04): : 425 - 434
  • [7] Bevacizumab and central nervous system (CNS) hemorrhage
    Nathalie Letarte
    Linda R. Bressler
    John L. Villano
    [J]. Cancer Chemotherapy and Pharmacology, 2013, 71 : 1561 - 1565
  • [8] PRIMARY CENTRAL NERVOUS SYSTEM (CNS) PHLEBITIS
    Keat, Karuna
    Levy, Stanley
    [J]. RHEUMATOLOGY, 2019, 58 : 40 - 40
  • [9] PATTERNS OF CENTRAL NERVOUS SYSTEM (CNS) MALFORMATIONS
    Ng, L.
    White, M.
    Murphy, J. F. A.
    [J]. IRISH JOURNAL OF MEDICAL SCIENCE, 2010, 179 : S221 - S222
  • [10] Pharmacogenomics of Central Nervous System (CNS) Drugs
    Cacabelos, Ramon
    [J]. DRUG DEVELOPMENT RESEARCH, 2012, 73 (08) : 461 - 476