Synthesis of pederic acid and related model studies

被引：9
|
作者：
Breitfelder, S [1 ]
Schuemacher, AC [1 ]
Rölle, T [1 ]
Kikuchi, M [1 ]
Hoffmann, RW [1 ]
机构：
[1] Univ Marburg, Fachbereich Chem, D-35032 Marburg, Germany
来源：
HELVETICA CHIMICA ACTA | 2004年 / 87卷 / 05期
关键词：
D O I：
10.1002/hlca.200490110
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
{[2-(Trimethylsilyl)ethoxy]methyl} (SEM)-protected pederic acid 16 was prepared by deriving the stereogenic center at C(7) from mannitol and those at C(2) and C(3) (mycalamide numbering) from trans-2,3-dimethyloxirane. Routes to pederamides involving a late oxygenation at C(7) were explored.
引用
收藏
页码：1202 / 1213
页数：12
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