Identification of therapeutically targetable genomic alterations in a cohort of patients with CUP using a hybrid-capture based next generation sequencing assay

被引：0
|
作者：
Menon, R. [1 ]
Mueller, J. [1 ]
Lakis, S. [1 ]
Hube, A. [1 ]
Bochtler, T. [2 ]
Wesseler, C. [3 ]
Griesinger, F. [4 ]
Loeffler, H. [2 ]
Langenbuch, T. [5 ]
Brandts, C. [6 ]
Garcia, A. P. [7 ]
Kraemer, A. [8 ]
Heuckmann, J. [1 ]
Heukamp, L. [1 ]
机构：
[1] NEO New Oncol GmbH, Cologne, Germany
[2] Univ Heidelberg Hosp, Med Clin 5, Heidelberg, Germany
[3] Asklepios Clin Harburg, Ctr Thorax, Harburg, Germany
[4] Pius Hosp Oldenburg, Internal Med Oncol, Oldenburg, Germany
[5] Onkol Praxis & Tagesklin, Hamburg, Germany
[6] JW Goethe Univ Hosp, Med Clin 2, Frankfurt, Germany
[7] Univ Navarra Clin, Pamplona, Spain
[8] Univ Heidelberg Hosp, Mol Hematol Oncol, Heidelberg, Germany
来源：
EUROPEAN JOURNAL OF CANCER | 2016年 / 69卷
关键词：
D O I：
10.1016/S0959-8049(16)32751-4
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
152
引用
收藏
页码：S55 / S55
页数：1
相关论文
共 50 条
  • [1] Comprehensive Assessment of Targetable Driver Alterations in Lung Adenocarcinomas Using a Clinical, Hybrid Capture-Based, Next-Generation Sequencing Assay
    Arcila, Maria
    Zehir, Ahmet
    Cheng, Donavan
    Yu, Helena
    Kris, Marc
    Drilon, Alexander
    Riely, Gregory
    Boger, Michael
    Ladanyi, Marc
    [J]. MODERN PATHOLOGY, 2015, 28 : 511A - 511A
  • [2] Comprehensive Assessment of Targetable Driver Alterations in Lung Adenocarcinomas Using a Clinical, Hybrid Capture-Based, Next-Generation Sequencing Assay
    Arcila, Maria
    Zehir, Ahmet
    Cheng, Donavan
    Yu, Helena
    Kris, Marc
    Drilon, Alexander
    Riely, Gregoty
    Berger, Michael
    Ladanyi, Marc
    [J]. LABORATORY INVESTIGATION, 2015, 95 : 511A - 511A
  • [3] Comprehensive Assessment of Targetable Somatic Alterations in Cytologic Cell Block Material Using a Clinical, Hybrid Capture-Based, Next-Generation Sequencing Assay
    Sadowska, Justyna
    Zehir, Ahmet
    Benayed, Ryma
    Ladanyi, Marc
    Lin, Oscar
    Arcila, Maria
    [J]. LABORATORY INVESTIGATION, 2015, 95 : 524A - 524A
  • [4] Comprehensive Assessment of Targetable Somatic Alterations in Cytologic Cell Block Material Using a Clinical, Hybrid Capture-Based, Next-Generation Sequencing Assay
    Sadowska, Justyna
    Zehir, Ahmet
    Benayed, Ryma
    Ladanyi, Marc
    Lin, Oscar
    Arcila, Maria
    [J]. MODERN PATHOLOGY, 2015, 28 : 524A - 524A
  • [5] Identification of novel and potentially targetable receptor tyrosine kinase alterations in colorectal carcinoma using a 341 gene hybrid capture-based next-generation sequencing assay.
    Hechtman, Jaclyn Frances
    Arcila, Maria E.
    Cheng, Donavan T.
    Solit, David B.
    Yaeger, Rona D.
    Hyman, David Michael
    Berger, Michael F.
    Shia, Jinru
    Vakiani, Efsevia
    Zehir, Ahmet
    Ladanyi, Marc
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2015, 33 (15)
  • [6] Next-Generation Sequencing for the Identification of Targetable Molecular Alterations in Cancer
    Dietrich, Martin F.
    Collins, Robert H.
    Gerber, David E.
    [J]. JAMA ONCOLOGY, 2016, 2 (01) : 132 - 133
  • [7] Identification Of Actionable Genomic Alterations In Hematologic Malignancies By a Clinical Next Generation Sequencing-Based Assay
    Lipson, Doron
    Nahas, Michelle K.
    Otto, Geoff A.
    Yelensky, Roman
    Abdel-Wahab, Omar
    Wang, Kai
    He, Jie
    Intlekofer, Andrew M.
    Rampal, Raajit K.
    Brennan, Timothy A.
    Knapp, Kristina M.
    Brennan, Kristina W.
    Young, Geneva
    Donahue, Amy L.
    Sanford, Eric M.
    Greenbowe, Joel R.
    Frampton, Garrett M.
    Fichtenholtz, Alex
    Young, Lauren E.
    Erlich, Rachel L.
    Parker, Alex
    Klimstra, David
    Dogan, Ahmet
    Ross, Jeffrey S.
    Armstrong, Scott A.
    Stephens, Philip J.
    van den Brink, Marcel R. M.
    Miller, Vincent A.
    Levine, Ross L.
    [J]. BLOOD, 2013, 122 (21)
  • [8] Targetable Genomic Alterations in KRAS Mutant Lung Adenocarcinoma by Targeted Next Generation Sequencing
    Arriola, E.
    Clave, S.
    Hardy-Werbin, M.
    Taus, A.
    Rocha, P.
    Chaib, I.
    Carcereny, E.
    Salido, M.
    Dalmases, A.
    Bellosillo, B.
    [J]. JOURNAL OF THORACIC ONCOLOGY, 2018, 13 (10) : S668 - S668
  • [9] Identification of Actionable Genomic Alterations Across Different Lymphoma Histologies Using a Comprehensive Next Generation Genomic Sequencing Clinical Assay
    Batlevi, Connie
    Moskowitz, Craig H.
    Zelenetz, Andrew D.
    Horwitz, Steven M.
    Palomba, Lia
    Gerecitano, John F.
    Copeland, Amanda R. M.
    Hamlin, Paul
    Matasar, Matthew J.
    Sauter, Craig S.
    Moskowitz, Alison J.
    Noy, Ariela
    Straus, David J.
    Portlock, Carol S.
    Mazzei, Colleen
    Pichardo, Janine D.
    Miller, Vincent
    Stephens, Phil J.
    He, Jie
    Feldstein, Julie T.
    Levine, Ross L.
    Dogan, Ahmet
    Younes, Anas
    [J]. BLOOD, 2014, 124 (21)
  • [10] Identifying targetable genetic alterations in advanced gastric cancer through broad, hybrid capture-based next generation sequencing.
    Liu, Dong
    Hou, Helei
    Zhang, Chuantao
    Zhou, Na
    Liu, Congmin
    Niu, Yurong
    Li, Tianjun
    Zhang, Jinping
    Li, Zhuokun
    Yang, Xiaonan
    Xie, Yonghui
    Zhang, Xiaochun
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (15)
12345