An EZ Mark to Miss

被引：13
|
作者：
Ho, Lena [2 ]
Crabtree, Gerald R. [1 ]
机构：
[1] Stanford Univ, Howard Hughes Med Inst, Sch Med, Stanford, CA 94305 USA
[2] Stanford Univ, Program Immunol, Sch Med, Stanford, CA 94305 USA
来源：
CELL STEM CELL | 2008年 / 3卷 / 06期
关键词：
D O I：
10.1016/j.stem.2008.11.007
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
Ezh2, the m ethyl transferase within Polycomb Repressive II Complexes, was thought to be essential for all H3K27me3 marks in embryonic stem cells (ESCs). Recently in Molecular Cell, Shen and colleagues (2008) revealed that EZH2 is dispensable for ESC derivation and self-renewal, and that EZH1 may unexpectedly compensate for its loss.
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页码：577 / 578
页数：2
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