Preparation and physicochemical of microemulsion based on macadamia nut oil

被引:2
|
作者
Tu, Xinghao [1 ,2 ]
Chen, Hong [2 ]
Du, Liqing [1 ]
机构
[1] Chinese Acad Trop Agr Sci, South Subtrop Crops Res Inst, Key Lab Trop Fruit Biol, Minist Agr, Zhanjiang 524091, Guangdong, Peoples R China
[2] Chinese Acad Agr Sci, Oil Crops Res Inst, Hubei Key Lab Lipid Chem & Nutr, Wuhan 430062, Hubei, Peoples R China
关键词
NANOSTRUCTURED LIPID CARRIERS; NANOPARTICLES SLN; DELIVERY;
D O I
10.1063/1.5029754
中图分类号
TE [石油、天然气工业]; TK [能源与动力工程];
学科分类号
0807 ; 0820 ;
摘要
The objective of the present work was to study the preparation, optimization and characteristic of nanostructured lipid carriers(NLCs) based on macadamia nut oil. NLC with various macadamia nut oil content were successfully prepared by an optimized microfluidization method using stearic acid as solid lipid and plutonic F68 as surfactant. As a result, NLC with particle size about 286nm were obtained, and the polydispersity index(PI) of all developed NLC were below 0.2 which indicate a narrow size distribution. Furthermore, the encapsulation efficiency and loading capability were investigated as well. Physical stability of NLC demonstrated that particles of system were stable at room temperature and low temperature. Differential scanning calorimetry(DSC) investigation show that the inner structure and recrystallinity of lipid matrix within NLC were greatly influenced by the content of macadamia nut oil.
引用
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页数:6
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