Effects of static magnetic field on human leukemic cell line HL-60

被引：64
|
作者：
Sabo, J
Mirossay, L
Horovcak, L
Sarissky, M
Mirossay, A
Mojzis, J
机构：
[1] Safarik Univ, Fac Med, Dept Med Biophys, Kosice 04011, Slovakia
[2] Safarik Univ, Fac Med, Dept Pharmacol, Kosice 04011, Slovakia
来源：
BIOELECTROCHEMISTRY | 2002年 / 56卷 / 1-2期
关键词：
HL-60; magnetic fields; chemotherapy; cytotoxicity;
D O I：
10.1016/S1567-5394(02)00027-0
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A number of structures with magnetic moments exists in living organisms that may be oriented by magnetic field. While most experimental efforts belong to the area of effects induced by weak and extremely low-frequency electromagnetic fields, we attempt to give an attention to the biological effects of strong static magnetic fields. The influence of static magnetic field (SMF) on metabolic activity of cells was examined. The metabolic activity retardation is observed in human leukemic cell line HL-60 exposed to I-T SMF for 72 h. The retardation effect was observed as well as in the presence of the mixture of the antineoplastic drugs 5 fluorouracil, cisplatin, doxorubicin and vincristine. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：227 / 231
页数：5
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