Local Anesthetic Systemic Toxicity

被引:60
|
作者
Dickerson, David M. [1 ]
Apfelbaum, Jeffrey L. [1 ]
机构
[1] Univ Chicago, Dept Anesthesia & Crit Care, Chicago, IL 60637 USA
关键词
local anesthetic toxicity; lipid emulsion; bupivacaine toxicity; acute pain; ambulatory surgery; REGIONAL ANESTHESIA; LIPID EMULSION; INTRAVASCULAR INJECTION; ULTRASOUND GUIDANCE; POSTOPERATIVE PAIN; BUPIVACAINE; EFFICACY; INFUSION; PHARMACOKINETICS; COMPLICATIONS;
D O I
10.1177/1090820X14543102
中图分类号
R61 [外科手术学];
学科分类号
摘要
Local anesthetic systemic toxicity (LAST) is a rare yet devastating complication from the administration of local anesthesia. The ability to recognize and treat LAST is critical for clinicians who administer these drugs. The authors reviewed the literature on the mechanism, treatment, and prevention of LAST, with the goal of proposing a practical method for its management
引用
收藏
页码:1111 / 1119
页数:9
相关论文
共 50 条
  • [1] Local anesthetic systemic toxicity
    Antel, Ryan
    Ingelmo, Pablo
    CANADIAN MEDICAL ASSOCIATION JOURNAL, 2022, 194 (37) : E1288 - E1288
  • [2] Local Anesthetic Systemic Toxicity
    Wadlund, Diana L.
    AORN JOURNAL, 2017, 106 (05) : 367 - 377
  • [3] Local anesthetic systemic toxicity
    Dillane, Derek
    Finucane, Brendan T.
    CANADIAN JOURNAL OF ANAESTHESIA-JOURNAL CANADIEN D ANESTHESIE, 2010, 57 (04): : 368 - 380
  • [4] Comments on "Local Anesthetic Systemic Toxicity"
    Onal, Ozkan
    Saltali, Ali Ozgul
    Apiliogullari, Seza
    AESTHETIC SURGERY JOURNAL, 2016, 36 (01) : NP37 - NP37
  • [5] Prevention of Local Anesthetic Systemic Toxicity
    Mulroy, Michael F.
    Hejtmanek, Michael R.
    REGIONAL ANESTHESIA AND PAIN MEDICINE, 2010, 35 (02) : 177 - 180
  • [6] Total Local Anesthetic Administered Is Integral to the Syndrome of Local Anesthetic Systemic Toxicity
    Petrar, Steven
    Montemurro, Trina
    ANESTHESIOLOGY, 2014, 121 (05) : 1130 - 1131
  • [7] Treatment of Local Anesthetic Systemic Toxicity (LAST)
    Weinberg, Guy L.
    REGIONAL ANESTHESIA AND PAIN MEDICINE, 2010, 35 (02) : 188 - 193
  • [8] A Rare Presentation of Local Anesthetic Systemic Toxicity
    Shenouda, S.
    Beier, J.
    Ayad, M.
    Aljilani, S.
    Thomas, J. M.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2024, 209
  • [9] Local Anesthetic Systemic Toxicity in a Nonoperative Location
    Cropsey, Christopher L.
    McEvoy, Matthew D.
    SIMULATION IN HEALTHCARE-JOURNAL OF THE SOCIETY FOR SIMULATION IN HEALTHCARE, 2015, 10 (05): : 326 - 328
  • [10] Local Anesthetic Systemic Toxicity: Perioperative Implications
    Fencl, Jennifer L.
    AORN JOURNAL, 2015, 101 (06) : 697 - 700