Rapid diagnosis of pulmonary tuberculosis by mycobacteriophage assay

被引：0
|
作者：
Butt, T [1 ]
Ahmad, RN [1 ]
Kazmi, SY [1 ]
Mahmood, A [1 ]
机构：
[1] Armed Forces Inst Pathol, Dept Microbiol, Rawalpindi, Pakistan
来源：
INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE | 2004年 / 8卷 / 07期
关键词：
tuberculosis; pulmonary; laboratory diagnostic test; mycobacteriophage assay;
D O I：
暂无
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
We evaluated FASTPlaqueTB(TM) , a recently introduced bacteriophage assay for rapid detection of Mycobacterium tuberculosis complex in sputum specimens, using 169 non-duplicate sputum specimens from patients suspected of pulmonary tuberculosis. The results of 160 specimens were analysed. FASTPlaqueTB(TM) assay detected tuberculosis in 77% (46/60) of culture-positive cases. Among the AFB smear-positive cases (n = 47) it had a sensitivity of 76% and specificity of 60% while among AFB smear-negative cases (n = 113) its sensitivity and specificity were 78% and 98%, respectively. The overall sensitivity and specificity of the technique were 77% and 96%, respectively, and the positive and negative predictive values were respectively 92% and 87%. The overall efficiency of the test was 89%. Test results were available in 48 h.
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页码：899 / 902
页数：4
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