Parallel synthesis of a series of subtype-selective NMDA receptor antagonists

被引：10
|
作者：
Gregory, TF [1 ]
Wright, JL
Wise, LD
Meltzer, LT
Serpa, KA
Konkoy, CS
Whittemore, ER
Woodward, RM
机构：
[1] Warner Lambert Parke Davis, Parke Davis Pharmaceut Res, Dept Chem, Ann Arbor, MI 48105 USA
[2] Warner Lambert Parke Davis, Parke Davis Pharmaceut Res, Dept Therapeut, Ann Arbor, MI 48105 USA
[3] CoCensys Inc, Irvine, CA 92618 USA
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2000年 / 10卷 / 06期
关键词：
D O I：
10.1016/S0960-894X(00)00035-4
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A series of 1-(heteroarylthioalkyl)-4-benzylpiperidines was rapidly synthesized through the use of parallel synthesis to investigate the binding affinity for the NR1A/2B receptor subtype. (C) 2000 Published by Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：527 / 529
页数：3
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