Development of MEM-288, a dual-transgene armed and conditionally replication-enhanced oncolytic adenovirus with potent systemic antitumor immunity

被引：0
|
作者：
Zheng, Hong [1 ]
Dai, Wenjie [1 ]
Antonia, Scott [2 ]
Cantwell, Mark J. [3 ]
Beg, Amer A. [1 ]
机构：
[1] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA
[2] Duke Canc Inst, Durham, NC USA
[3] Memgen LLC, Houston, TX USA
来源：
CANCER RESEARCH | 2020年 / 80卷 / 16期
关键词：
D O I：
10.1158/1538-7445.AM2020-4578
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
4578
引用
收藏
页数：2
相关论文
共 2 条
  • [1] Defining anti-tumor immune stimulatory mechanisms of MEM-288, a CD40 ligand and IFN-beta dual-transgene armed oncolytic adenovirus.
    Zheng, Hong
    Powell, Chase D.
    Antonia, Scott
    Cantwell, Mark J.
    Perez, Bradford A.
    Beg, Amer A.
    CANCER RESEARCH, 2021, 81 (13)
  • [2] Oncolytic Adenovirus Armed with a Type I Interferon Exerts Systemic Antitumor Immunity in Immunocompetent Replication-Permissive Models
    Inoko, Kazuho
    Shinoda, Shuhei
    Mancipe, Natalia Calixto
    Romanenko, Margarita
    Robert, Sacha
    Sato-Dahlman, Mizuho
    Jacobsen, Kari
    Noguchi, Takuro
    Yamamoto, Masato
    Davydova, Julia
    MOLECULAR THERAPY, 2024, 32 (04) : 197 - 197
1