Multi-omics profiling can predict for relapse and response to brexucabtagene autoleucel CAR-Tcell therapy in patients with mantle cell lymphoma

被引：0
|
作者：
Jiang, Vivian Changying [1 ]
Hao, Dapeng [1 ]
Jain, Preetesh [1 ]
Li, Yijing [1 ]
Cai, Qingsong [1 ]
Liu, Yang [1 ]
Che, Yuxuan [1 ]
Vargas, Jovanny [1 ]
Yao, Yixin [1 ]
Nie, Lei [1 ]
Dai, Enyu [1 ]
Han, Guangchun [1 ]
Wang, Ruiping [1 ]
Rai, Kunal [1 ]
Futreal, Andrew [1 ]
Flowers, Christopher [1 ]
Wang, Linghua [1 ]
Wang, Michael [1 ]
机构：
[1] Univ Texas MD Anderson Canc Ctr, Houston, TX USA
来源：
CANCER RESEARCH | 2022年 / 82卷 / 12期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
771
引用
收藏
页数：2
相关论文
共 22 条
  • [1] Bridging Radiotherapy prior to Brexucabtagene Autoleucel CAR T-Cell Therapy in Mantle Cell Lymphoma
    Figura, N.
    Sim, A.
    Dahiya, S.
    Lutfi, F.
    Rapoport, A.
    Mohindra, P.
    Dohm, A.
    Chavez, J.
    Shah, B.
    Khimani, F.
    Lazaryan, A.
    Davila, M.
    Bachmeier, C.
    Nishihori, T.
    Liu, H.
    Kim, S.
    Locke, F.
    Jain, M.
    Robinson, T.
    RADIOTHERAPY AND ONCOLOGY, 2021, 161 : S894 - S895
  • [2] Outcomes and management of patients with mantle cell lymphoma after progression on brexucabtagene autoleucel therapy
    Jain, Preetesh
    Nastoupil, Loretta
    Westin, Jason
    Lee, Hun Ju
    Navsaria, Lucy
    Steiner, Raphael E.
    Ahmed, Sairah
    Moghrabi, Omar
    Oriabure, Onyeka
    Chen, Wendy
    Badillo, Maria
    Flowers, Christopher R.
    Wang, Michael L.
    BRITISH JOURNAL OF HAEMATOLOGY, 2021, 192 (02) : E38 - E42
  • [3] Analysis of Outcomes and Predictors of Response in Patients with Relapsed Mantle Cell Lymphoma Treated with Brexucabtagene Autoleucel
    Romancik, Jason T.
    Goyal, Subir
    Gerson, James N.
    Ballard, Hatcher J.
    Sawalha, Yazeed
    Bond, David A.
    Rogalski, Michael Joseph
    Greenwell, Irl Brian
    van Besien, Koen
    Yamshon, Samuel
    Karmali, Reem
    Nizamuddin, Imran
    Torka, Pallawi
    Chow, Victor A.
    Shadman, Mazyar
    Ghosh, Nilanjan
    Moyo, Tamara K.
    Fenske, Timothy S.
    Rezazadeh, Alexandra
    Grover, Natalie S.
    Maddocks, Kami J.
    Jacobson, Caron
    Cohen, Jonathon B.
    BLOOD, 2021, 138
  • [4] Real-world experience with CAR-T therapy with Brexucabtagene Autoleucel for advanced relapsed mantle cell lymphoma
    Heini, A.
    Kronig, M. -N.
    Bacher, U.
    Taleghani, B. Mansouri
    Novak, U.
    Pabst, T.
    SWISS MEDICAL WEEKLY, 2021, 151 : 2 - 2
  • [5] Efficacy and safety of brexucabtagene autoleucel CAR T-cell therapy with BTK inhibitors in the treatment of relapsed mantle cell lymphoma with central nervous system involvement
    Lionel, Anath C.
    Gurumurthi, Ashwath
    Fetooh, Ahmed
    Eldaya, Rami
    Ahmed, Sairah
    Iyer, Swaminathan P.
    Nastoupil, Loretta J.
    Westin, Jason
    Nair, Ranjit
    Fayad, Luis
    Malpica, Luis
    Tummala, Sudhakar
    Flowers, Christopher
    Neelapu, Sattva S.
    Wang, Michael L.
    Jain, Preetesh
    LEUKEMIA & LYMPHOMA, 2024, 65 (05) : 669 - 673
  • [6] Uncommon Viral Infections in Patients Treated With CAR-T Cell Therapy: Concurrent Adenovirus and BK Virus Infection in a Mantle Cell Lymphoma Patient Within 30 Days After Receiving Brexucabtagene Autoleucel
    Tregubenko, Polina
    Abdelhakim, Haitham
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2022, 22 : S442 - S443
  • [7] The CAR-Hematotox Score Identifies Patients at High Risk for Hematological Toxicity, Infections and Poor Clinical Outcomes Following Brexucabtagene Autoleucel in Relapsed/Refractory Mantle Cell Lymphoma
    Rejeski, Kai
    Wang, Yucai
    Albanyan, Omar
    Munoz, Javier L.
    Sesques, Pierre
    Iacoboni, Gloria
    Corral, Lucia Lopez
    Mohty, Razan
    Dreyling, Martin
    Locke, Frederick L.
    Barba, Pere
    Bachy, Emmanuel
    Lin, Yi
    Subklewe, Marion
    Jain, Michael D.
    BLOOD, 2022, 140
  • [8] Multi-Omics Reveal Plasma Molecular Signatures of B-ALL Patients during CAR-T Cell Therapy
    Wu, Jianghua
    Tang, Lu
    Du, Mengyi
    Li, Chenggong
    Kou, Haiming
    Jiang, Huiwen
    Luo, Wenjing
    Zhang, Yinqiang
    Huang, Zhongpei
    Liao, Danying
    Xiong, Wei
    Mei, Heng
    Hu, Yu
    BLOOD, 2022, 140 : 7384 - 7385
  • [9] Integration of Single-cell Multi-omics Profiling for Investigating Treatment Response to Tumor Necrosis Factor Alpha Inhibitors in Patients with Axial Spondyloarthritis
    Lee, Seulkee
    Park, Jae Soon
    Ignatova, Elizaveta
    Kang, Seonyoung
    Kim, Hyungjin
    Lee, Jaejoon
    Choi, Jung Kyoon
    Cha, Hoon-Suk
    ARTHRITIS & RHEUMATOLOGY, 2024, 76 : 4762 - 4765
  • [10] Several factors that predict the outcome of large B-cell lymphoma patients who relapse/progress after chimeric antigen receptor (CAR) T-cell therapy can be identified before cell administration
    Sykorova, Alice
    Folber, Frantisek
    Polgarova, Kamila
    Mocikova, Heidi
    Duras, Juraj
    Steinerova, Katerina
    Obr, Ales
    Heindorfer, Adriana
    Ladicka, Miriam
    Lukacova, Lubica
    Cellarova, Erika
    Plamenova, Ivana
    Belada, David
    Janikova, Andrea
    Trneny, Marek
    Jancarkova, Tereza
    Prochazka, Vit
    Vranovsky, Andrej
    Kralikova, Margareta
    Vydra, Jan
    Smolej, Lukas
    Drgona, Lubos
    Sedmina, Martin
    Cermakova, Eva
    Pytlik, Robert
    CANCER MEDICINE, 2024, 13 (17):
123