Psychiatrists' Views of the Genetic Bases of Mental Disorders and Behavioral Traits and Their Use of Genetic Tests

被引:15
|
作者
Klitzman, Robert [1 ]
Abbate, Kristopher J. [1 ]
Chung, Wendy K. [1 ]
Marder, Karen [1 ]
Ottman, Ruth [1 ]
Taber, Katherine Johansen [2 ]
Leu, Cheng-Shiun [3 ]
Appelbaum, Paul S. [1 ,4 ]
机构
[1] Columbia Univ, Med Ctr, New York, NY 10032 USA
[2] Amer Med Assoc, Chicago, IL 60610 USA
[3] Columbia Univ, HIV Ctr Clin & Behav Studies, New York, NY 10032 USA
[4] New York State Psychiat Inst & Hosp, New York, NY 10032 USA
关键词
Genomics; epigenetics; genetic testing; decision making; etiology; ENVIRONMENTAL-INFLUENCES; TWIN; HERITABILITY; ATTITUDES; PHYSICIANS; TOLERANCE; AMBIGUITY; VARIANTS; COMMON; RATES;
D O I
10.1097/NMD.0000000000000154
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We examined how 372 psychiatrists view genetic aspects of mental disorders and behaviors and use genetic tests (GTs). Most thought that the genetic contribution was moderate/high for bipolar disorder, schizophrenia, depression, Alzheimer's, intelligence, creativity, anxiety, and suicidality. In the past 6 months, 14.1% ordered GTs, 18.3% discussed prenatal testing with patients, 36.0% initiated discussions about other GTs, 41.6% had patients ask about GTs, and 5.3% excluded GT results from patient records. Many thought that GTs; were available for schizophrenia (24.3%) and major depression (19.6%). Women were more likely to report that patients asked about GTs; and were less certain about the degree of genetic contribution to several disorders. Psychiatrists perceive strong genetic bases for numerous disorders and traits, and many have discussed and ordered tests for GTs, but have relatively limited knowledge about available tests. These data suggest possible sex differences in psychiatrists' beliefs about genetic contributions to disorders and have implications for future research, education, policy, and care.
引用
收藏
页码:530 / 538
页数:9
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