The electroretinogram (ERG) provides information about outer retina function in both clinical and research applications. ERG components elicited by light increments and decrements can be separated using a long-flash paradigm in which periods of light ON and OFF are alternated. Here, the ON-OFF ERG is combined with a silent substitution technique to elicit responses from individual cone photoreceptor classes by modulating the intensities of three color lights between the two periods. The results focus on the short wavelength ( S) cone pathways since they are vulnerable to disease and because there are many unanswered questions about S-cone ON and OFF circuitry. (c) 2014 Optical Society of America
机构:
Saitama Med Univ, Fac Med, Dept Physiol, 38 Morohongo, Moroyama, Saitama, JapanSaitama Med Univ, Fac Med, Dept Physiol, 38 Morohongo, Moroyama, Saitama, Japan
Hirasawa, Hajime
Miwa, Naofumi
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Saitama Med Univ, Fac Med, Dept Physiol, 38 Morohongo, Moroyama, Saitama, JapanSaitama Med Univ, Fac Med, Dept Physiol, 38 Morohongo, Moroyama, Saitama, Japan
Miwa, Naofumi
Watanabe, Shu-Ichi
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Saitama Med Univ, Fac Med, Dept Physiol, 38 Morohongo, Moroyama, Saitama, JapanSaitama Med Univ, Fac Med, Dept Physiol, 38 Morohongo, Moroyama, Saitama, Japan
机构:
Michigan State Univ, Coll Vet Med, Dept Small Anim Clin Sci, 736 Wilson Rd,D208, E Lansing, MI 48824 USAMichigan State Univ, Coll Vet Med, Dept Small Anim Clin Sci, 736 Wilson Rd,D208, E Lansing, MI 48824 USA
Pasmanter, Nate
Petersen-Jones, Simon M. M.
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Michigan State Univ, Coll Vet Med, Dept Small Anim Clin Sci, 736 Wilson Rd,D208, E Lansing, MI 48824 USAMichigan State Univ, Coll Vet Med, Dept Small Anim Clin Sci, 736 Wilson Rd,D208, E Lansing, MI 48824 USA