Virulence of Pertactin-Negative Bordetella pertussis Isolates from Infants, France

被引:51
|
作者
Bodilis, Helene [2 ]
Guiso, Nicole [1 ]
机构
[1] Inst Pasteur, F-75724 Paris 15, France
[2] CNRS, F-75700 Paris, France
关键词
STRAINS; VACCINE;
D O I
10.3201/1903.121475
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Bordetella pertussis isolates that do not express pertactin (PRN) are increasing in regions where acellular pertussis vaccines have been used for >7 years. We analyzed data from France and compared clinical symptoms among infants <6 months old infected by PRN-positive or PRN-negative isolates. No major clinical differences were found between the 2 groups.
引用
收藏
页码:471 / 474
页数:4
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