Proximal Tubule Cell-Specific Adenoviral Transfer of an Intracellular Angiotensin II Fusion Protein Elevates Blood Pressure by Activating AT1 Receptors in Rats

被引:0
|
作者
Li, Xiao C. [1 ]
Cook, Julie L. [2 ]
Rubera, Isabelle [3 ]
Zhang, Fan [1 ]
Tauc, Michel [3 ]
Zhuo, Jia L. [1 ]
机构
[1] Henry Ford Hosp, Detroit, MI 48202 USA
[2] Ochsner Clin Fdn, New Orleans, LA USA
[3] Univ Nice Sophia Antipolis, Parc Valrose, France
关键词
D O I
暂无
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
引用
收藏
页码:E73 / E73
页数:1
相关论文
共 15 条
  • [1] AT1 angiotensin receptors in the proximal tubule of the kidney are essential for blood pressure regulation
    Gurley, Susan B.
    Allen, Andrew M.
    Haase, Volker H.
    Snouwaert, John N.
    Koller, Beverly H.
    Le, Thu H.
    Coffman, Thomas M.
    HYPERTENSION, 2008, 52 (04) : E47 - E47
  • [2] Role of internalized angiotensin II and AT1 receptors in intracellular calcium mobilization in cultured proximal tubule cells
    Zhuo, JL
    Garvin, JL
    Carretero, OA
    HYPERTENSION, 2003, 42 (03) : 388 - 388
  • [3] Intrarenal transfer of an intracellular fluorescent fusion of angiotensin II selectively in proximal tubules increases blood pressure in rats and mice
    Li, Xiao C.
    Cook, Julia L.
    Rubera, Isabelle
    Tauc, Michel
    Zhang, Fan
    Zhuo, Jia L.
    AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2011, 300 (05) : F1076 - F1088
  • [4] Proximal tubule-dominant transfer of AT1a receptors induces blood pressure responses to intracellular angiotensin II in AT1a receptor-deficient mice
    Li, Xiao C.
    Zhuo, Jia L.
    AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 2013, 304 (08) : R588 - R598
  • [5] Angiotensin II regulation of AT1 and D3 dopamine receptors in renal proximal tubule cells of spontaneously hypertensive rats
    Zeng, CY
    Yu, PY
    Eisner, GM
    Jose, PA
    HYPERTENSION, 2002, 40 (03) : 379 - 379
  • [6] Overexpression of an Intracellular Angiotensin II Fusion Protein Selectively in the Mitochondria of the Proximal Tubules Elevates Blood Pressure in Mice via AT1a Receptor-mediated Mitochondrial Respiratory and Glycolysis Stress
    Li, Xiao C.
    Soleimani, Manoocher
    Hoang Nguyen
    Li, Hong
    Zhuo, Jia L.
    HYPERTENSION, 2016, 68
  • [7] Proximal Tubule- Specific Expression of AT1a Receptors in the Kidney Mediates Extracellular and Intracellular Angiotensin II-Induced Blood Pressure Responses in AT1a Receptor-Knockout Mice
    Li, Xiao C.
    Cook, Julia L.
    Zhang, Fan
    Gu, Victor
    Zhuo, Jia L.
    HYPERTENSION, 2010, 56 (05) : E64 - E64
  • [8] Expression of cell cycle proteins in blood vessels of angiotensin II-infused rats -: Role of AT1 receptors
    Diep, QN
    El Mabrouk, M
    Touyz, RM
    Schiffrin, EL
    HYPERTENSION, 2001, 37 (02) : 604 - 608
  • [9] Angiotensin II AT2 Receptors Decrease AT1 Receptors Expression and Function via NO/cGMP/Sp1 in Renal Proximal Tubule Cells From Wistar-Kyoto Rats
    Yang, Jian
    Ren, Hongmei
    Chen, Caiyu
    He, Duofen
    Han, Yu
    Yu, Changqing
    Zhou, Lin
    Jose, Pedro
    Zeng, Chunyu
    HYPERTENSION, 2011, 58 (05) : E53 - E53
  • [10] Proximal Tubule-specific Deletion Of Angiotensin Ii Type 1a Receptors In The Kidney Lowers Basal Blood Pressure And Attenuates Angiotensin Ii-induced Hypertension By Increasing Glomerular Filtration And The Pressure-natriuresis Response.
    Li, Xiao C.
    Leite, Ana P.
    Zhang, Liang
    Zhuo, Jia L.
    HYPERTENSION, 2020, 76