ULTRASOUND DOPPLER MONITORING OF SOFT TISSUES IN VITRO AND TISSUE PHANTOMS HEATING AND THERMAL DESTRUCTION INDUCED BY ACOUSTIC REMOTE PALPATION

被引:4
|
作者
Girnyk, S. A. [1 ]
Barannik, A. E. [1 ]
Tovstiak, V. V. [1 ]
Tolstoluzhsky, D. A. [1 ]
Barannik, E. A. [1 ]
机构
[1] Kharkov Natl Univ, Kharkov, Ukraine
来源
ULTRASOUND IN MEDICINE AND BIOLOGY | 2009年 / 35卷 / 05期
关键词
ARP; Doppler probing; Shear strain; Viscoelasticity; HIFU; Hyperthermia; Coagulation; Phase transition; FOCUSED ULTRASOUND; RADIATION FORCE; VISCOSITY;
D O I
10.1016/j.ultrasmedbio.2008.11.008
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
The rise of shear strain value under temperature increase in biological tissue samples in vitro and tissue phantoms was studied and the range of shear modulus and viscosity calculated. It has been shown that the acoustic radiation force-based methods with the usage of ultrasound Doppler probing provides the potential ability of noninvasive real-time monitoring of tissues' ultrasound thermal destruction process. At that, the thermal destruction is possible under action of wave beam that creates the radiation force and local tissue displacements so that tissue ablation and acoustic remote palpation could be realized by means of the same ultrasound transducer. The experiments were performed using gelatin-based tissue-mimicking phantoms and freshly excised samples of bovine muscle tissue. It was determined also that fluctuating pattern of detected displacement amplitude variation is the indicator of the phase transitions beginning in the heated field of soft tissue or tissue phantom. (E-mail: Evgenij.A.Barannik@univer.kharkov.ua; barannik@pht.univer.kharkov.ua) (C) 2009 World Federation for Ultrasound in Medicine & Biology.
引用
收藏
页码:764 / 772
页数:9
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