HCOOH, an Inexpensive, Convenient, and Practical 13C NMR Solvent for Strong Polar Amino Acids and their Derivatives

被引：3
|
作者：
Chen, Ning
Xu, Jiaxi [1 ]
机构：
[1] Beijing Univ Chem Technol, State Key Lab Chem Resource Engn, Beijing 100029, Peoples R China
来源：
LETTERS IN ORGANIC CHEMISTRY | 2009年 / 6卷 / 04期
基金：
北京市自然科学基金; 中国国家自然科学基金;
关键词：
Amino acid; Carbon-13 nuclear magnetic resonance spectrum; Peptide; N-protected amino acid; Polar organic compound; Solvent; SUBSTITUTED TAURINES;
D O I：
10.2174/157017809788489945
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Amino acids and some of their derivatives are strong polar organic compounds. Non-deuterated formic acid was used as an inexpensive, convenient, and practical C-13 NMR solvent for these strong polar compounds. It was also used to determine hydroxyl carboxylic acids and nucleosides. C-13 NMR chemical shifts in formic acid of representative examples and widely used solvents in organic reactions were provided. Formic acid is a counterpart to commonly used perdeuterated chloroform, dimethyl sulfoxide, methanol, and water.
引用
收藏
页码：349 / 353
页数：5
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