A Frailty Scale Predicts Outcomes of Patients with Newly Diagnosed Multiple Myeloma Who Are Ineligible for Transplant Treated with Continuous Lenalidomide Plus Low-Dose Dexamethasone on the First Trial

被引:12
|
作者
Facon, Thierry [1 ]
Hulin, Cyrille [2 ]
Dimopoulos, Meletios A. [3 ]
Belch, Andrew [4 ]
Meuleman, Nathalie [5 ]
Mohty, Mohamad [6 ]
Chen, Wen-Ming [7 ]
Kim, Kihyun [8 ]
Zamagni, Elena [9 ]
Rodriguez-Otero, Paula [10 ]
Renwick, William [11 ]
Rose, Christian [12 ]
Tempescul, Adrian [13 ]
Palumbo, Antonio [14 ]
Guo, Shien [15 ]
Sturniolo, Michael [16 ]
Ervin-Haynes, Annette [16 ]
Fermand, Jean-Paul [17 ]
机构
[1] CHRU Lille, Hop Claude Huriez, Malad Sang, F-59037 Lille, France
[2] CHU BORDEAUX, Bordeaux, France
[3] Univ Athens, Sch Med, Athens 11528, Greece
[4] Cross Canc Inst, Edmonton, AB T6G 1Z2, Canada
[5] Univ Libre Bruxelles, Jules Bordet Insitute, Dept Hematol, Brussels, Belgium
[6] St Antoine Hosp, Dept Haematol, Paris, France
[7] Beijing Chaoyang Hosp, Beijing, Peoples R China
[8] Sungkyunkwan Univ, Samsung Med Ctr, Seoul, South Korea
[9] Azienda Osped Univ, Bologna, Italy
[10] Univ Navarra Clin, Pamplona, Spain
[11] Western Hlth, St Albans, Australia
[12] Hop St Vincent, Dept Hematol, Lille, France
[13] CHU Brest, Dept Hematol, F-29285 Brest, France
[14] Univ Turin, Turin, Italy
[15] Evidera, Boston, MA USA
[16] Celgene Corp, Summit, NJ USA
[17] Hop St Louis, AP HP, Serv Immunohematol, Paris, France
关键词
D O I
10.1182/blood.V126.23.4239.4239
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页数:4
相关论文
共 50 条
  • [1] A FRAILTY SCALE PREDICTS OUTCOMES IN TRANSPLANT-INELIGIBLE PATIENTS WITH NEWLY DIAGNOSED MULTIPLE MYELOMA TREATED WITH CONTINUOUS LENALIDOMIDE PLUS LOW-DOSE DEXAMETHASONE IN THE FIRST (MM-020) TRIAL
    Facon, T.
    Hulin, C.
    Dimopoulos, M. A.
    Belch, A.
    Meuleman, N.
    Mohty, M.
    Chen, W. M.
    Kim, K.
    Zamagni, E.
    Rodriguez-Otero, P.
    Renwick, W.
    Rose, C.
    Tempescul, A.
    Boyle, E.
    Palumbo, A.
    Guo, S.
    Monzini, M. S.
    Sturniolo, M.
    Ervin-Haynes, A.
    Fermand, J. P.
    HAEMATOLOGICA, 2016, 101 : 258 - 259
  • [2] Impact of Cytogenetics on Outcomes of Transplant-Ineligible Patients with Newly Diagnosed Multiple Myeloma Treated with Continuous Lenalidomide Plus Low-Dose Dexamethasone in the First (MM-020) Trial
    Avet-Loiseau, Herve
    Hulin, Cyrille
    Benboubker, Lofti
    Dimopoulos, Meletios A.
    Belch, Andrew
    Reece, Donna
    Catalano, John
    Pinto, Antonio
    Ludwig, Heinz
    Bahlis, Nizar J.
    Cavo, Michele
    Attal, Michel
    Moreau, Philippe
    Qiu, Lugui
    LeBlanc, Richard
    Schots, Rik
    Rajkumar, S. Vincent
    Marek, Jennifer
    Chen, Guang
    Yiu, Wai
    Ervin-Haynes, Annette
    Facon, Thierry
    BLOOD, 2015, 126 (23)
  • [3] THE FIRST TRIAL: ANALYSIS OF THE ASIAN SUBGROUP OF TRANSPLANT-INELIGIBLE PATIENTS WITH NEWLY DIAGNOSED MULTIPLE MYELOMA TREATED WITH CONTINUOUS LENALIDOMIDE AND LOW-DOSE DEXAMETHASONE
    Lu, J.
    Lee, J. H.
    Huang, S. Y.
    Qiu, L.
    Lee, J. J.
    Liu, T.
    Yoon, S. S.
    Kim, K.
    Shen, Z. X.
    Eom, H. S.
    Chen, W. M.
    Min, C. K.
    Kim, H. J.
    Lee, J. O.
    Kwak, J. Y.
    Yiu, W.
    Chen, G.
    Ervin-Haynes, A.
    Hulin, C.
    Facon, T.
    HAEMATOLOGICA, 2016, 101 : 548 - 549
  • [4] Continuous Treatment with Lenalidomide and Low-Dose Dexamethasone in Transplant-Ineligible Patients with Newly Diagnosed Multiple Myeloma in Asia: Subanalysis of the First Trial
    Lu, Jin
    Lee, Jae Hoon
    Huang, Shang-Yi
    Qiu, Lugui
    Lee, Je-Jung
    Liu, Ting
    Yoon, Sung-Soo
    Kim, Kihyun
    Shen, Zhi Xiang
    Eom, HyeonSeok
    Chen, Wenming
    Min, Chang-Ki
    Kim, Hyo Jung
    Lee, Jeong Ok
    Kwak, Jae Yong
    Yiu, Wai
    Chen, Guang
    Haynes, Annette Ervin
    Hulin, Cyrille
    Facon, Thierry
    BLOOD, 2015, 126 (23)
  • [5] Continuous treatment with lenalidomide and low-dose dexamethasone in transplant-ineligible patients with newly diagnosed multiple myeloma in Asia: subanalysis of the FIRST trial
    Lu, Jin
    Lee, Jae H.
    Huang, Shang-Yi
    Qiu, Lugui
    Lee, Je-Jung
    Liu, Ting
    Yoon, Sung-Soo
    Kim, Kihyun
    Shen, Zhi X.
    Eom, Hyeon S.
    Chen, Wen M.
    Min, Chang K.
    Kim, Hyo J.
    Lee, Jeong O.
    Kwak, Jae Y.
    Yiu, Wai
    Chen, Guang
    Ervin-Haynes, Annette
    Hulin, Cyrille
    Facon, Thierry
    BRITISH JOURNAL OF HAEMATOLOGY, 2017, 176 (05) : 743 - 749
  • [6] A simplified frailty scale predicts outcomes in transplant-ineligible patients with newly diagnosed multiple myeloma treated in the FIRST (MM-020) trial
    Facon, Thierry
    Dimopoulos, Meletios A.
    Meuleman, Nathalie
    Belch, Andrew
    Mohty, Mohamad
    Chen, Wen-Ming
    Kim, Kihyun
    Zamagni, Elena
    Rodriguez-Otero, Paula
    Renwick, William
    Rose, Christian
    Tempescul, Adrian
    Boyle, Eileen
    Manier, Salomon
    Attal, Michel
    Moreau, Philippe
    Macro, Margaret
    Leleu, Xavier
    Chretien, Marie Lorraine
    Ludwig, Heinz
    Guo, Shien
    Sturniolo, Michael
    Tinel, Antoine
    Monzini, Mara Silvia
    Costa, Bruno
    Houck, Vanessa
    Hulin, Cyrille
    Mary, Jean Yves
    LEUKEMIA, 2020, 34 (01) : 224 - 233
  • [7] A simplified frailty scale predicts outcomes in transplant-ineligible patients with newly diagnosed multiple myeloma treated in the FIRST (MM-020) trial
    Thierry Facon
    Meletios A. Dimopoulos
    Nathalie Meuleman
    Andrew Belch
    Mohamad Mohty
    Wen-Ming Chen
    Kihyun Kim
    Elena Zamagni
    Paula Rodriguez-Otero
    William Renwick
    Christian Rose
    Adrian Tempescul
    Eileen Boyle
    Salomon Manier
    Michel Attal
    Philippe Moreau
    Margaret Macro
    Xavier Leleu
    Marie Lorraine Chretien
    Heinz Ludwig
    Shien Guo
    Michael Sturniolo
    Antoine Tinel
    Mara Silvia Monzini
    Bruno Costa
    Vanessa Houck
    Cyrille Hulin
    Jean Yves Mary
    Leukemia, 2020, 34 : 224 - 233
  • [8] Continuous lenalidomide and low-dose dexamethasone in patients with transplant-ineligible newly diagnosed MM: FIRST trial subanalysis of Canadian/US patients
    Belch, Andrew
    Bahlis, Nizar
    White, Darrell
    Cheung, Matthew
    Chen, Christine
    Shustik, Chaim
    Song, Kevin
    Tosikyan, Axel
    Dispenzieri, Angela
    Anderson, Kenneth
    Brown, Diane
    Robinson, Suzanne
    Srinivasan, Shankar
    Facon, Thierry
    CANCER MEDICINE, 2020, 9 (23): : 8923 - 8930
  • [9] Daratumumab plus lenalidomide and dexamethasone in transplant-ineligible newly diagnosed multiple myeloma: frailty subgroup analysis of MAIA
    Facon, Thierry
    Cook, Gordon
    Usmani, Saad Z.
    Hulin, Cyrille
    Kumar, Shaji
    Plesner, Torben
    Touzeau, Cyrille
    Bahlis, Nizar J.
    Basu, Supratik
    Nahi, Hareth
    Goldschmidt, Hartmut
    Quach, Hang
    Mohty, Mohamad
    Venner, Christopher P.
    Weisel, Katja
    Raje, Noopur
    Hebraud, Benjamin
    Belhadj-Merzoug, Karim
    Benboubker, Lotfi
    Decaux, Olivier
    Manier, Salomon
    Caillot, Denis
    Ukropec, Jon
    Pei, Huiling
    Van Rampelbergh, Rian
    Uhlar, Clarissa M.
    Kobos, Rachel
    Zweegman, Sonja
    LEUKEMIA, 2022, 36 (04) : 1066 - 1077
  • [10] Daratumumab plus lenalidomide and dexamethasone in transplant-ineligible newly diagnosed multiple myeloma: frailty subgroup analysis of MAIA
    Thierry Facon
    Gordon Cook
    Saad Z. Usmani
    Cyrille Hulin
    Shaji Kumar
    Torben Plesner
    Cyrille Touzeau
    Nizar J. Bahlis
    Supratik Basu
    Hareth Nahi
    Hartmut Goldschmidt
    Hang Quach
    Mohamad Mohty
    Christopher P. Venner
    Katja Weisel
    Noopur Raje
    Benjamin Hebraud
    Karim Belhadj-Merzoug
    Lotfi Benboubker
    Olivier Decaux
    Salomon Manier
    Denis Caillot
    Jon Ukropec
    Huiling Pei
    Rian Van Rampelbergh
    Clarissa M. Uhlar
    Rachel Kobos
    Sonja Zweegman
    Leukemia, 2022, 36 : 1066 - 1077