Parallel findings in the adult children of alcoholics (ACOA) and child abuse literatures are integrated and extended by assessing long-term adjustment and childhood histories of parental alcoholism and sexual, physical, and emotional abuse in college students (N = 333). Abuse histories were most strongly related to adult symptom distress and social maladjustment. Parental alcoholism had no independent effects when controlling for abuse history. Parental alcoholism interacted with abuse history in relation to social adjustment, exacerbating the effects of emotional abuse. This study adds to a growing literature calling for move complex models of ACOA development that can account for the diversity of this population.