Electromagnetic induction detector with a vertical coil for capillary electrophoresis and microfluidic chip

We report a new electromagnetic induction detector with two vertical inductors for capillary electrophoresis and microfluidic chip capillary electrophoresis. Compared with currently available detection methods, this new detector has several advantages, including simple construction, no complicated elements, ease of assembly and operation, and potential for universal applications. The conditions affecting the response of the detector, including the number of coil turns, the frequency and the effective voltage, were optimized. Its feasibility and performance were demonstrated by analyzing inorganic ions. The new detector showed a well-defined correlation between the ion concentrations and the responses (r = 0.993-0.998), with a detection limit of 5.6 mu mol L(-1) for Mn(2+), as well as good reproducibility and stability for both CE and microfluidic chip CE. (C) 2009 Elsevier B.V. All rights reserved.