Antifungal resistance in pathogenic fungi

被引：190
|
作者：
Perea, S
Patterson, TF
机构：
[1] Univ Texas, Hlth Sci Ctr, Div Infect Dis, Dept Med, San Antonio, TX 78229 USA
[2] S Texas Vet Hlth Care Syst, Audie Murphy Div, San Antonio, TX USA
来源：
CLINICAL INFECTIOUS DISEASES | 2002年 / 35卷 / 09期
关键词：
D O I：
10.1086/344058
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Pathogenic fungi are the cause of life-threatening infections in an increasing number of immunocompromised patients. The intrinsic resistance to antifungal therapy observed in some genera, along with the development of resistance during treatment in others, is becoming a major problem in the management of these diseases. We reviewed the epidemiology of the most common systemic fungal infections for which antifungal resistance is a potential problem, the mechanisms of antifungal resistance, the correlation between in vitro susceptibility testing and clinical outcome, and the clinical implications of antifungal resistance.
引用
收藏
页码：1073 / 1080
页数：8
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