Analgesic and anti-inflammatory effects of the aqueous extract of leaves of Persea americana Mill (Lauraceae)

被引:108
|
作者
Adeyemi, OO [1 ]
Okpo, SO [1 ]
Ogunti, OO [1 ]
机构
[1] Univ Lagos, Coll Med, Dept Pharmacol, Lagos, Nigeria
关键词
Persea americana; anti-inflammatory; analgesic effects;
D O I
10.1016/S0367-326X(02)00118-1
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The aqueous extract of Persea americana leaves produced a dose-dependent inhibition of both phases of formalin pain test in mice, a reduction in mouse writhing induced by acetic acid and an elevation of pain threshold in the hot plate test in mice. The extract also produced a dose-dependent inhibition of carrageenan-induced rat paw oedema. The results obtained indicate that the extract possesses analgesic and anti-inflammatory effects. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:375 / 380
页数:6
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