PRODUCTION OF HOMOLOGOUS LIVE ATTENUATED CELL CULTURE VACCINE FOR THE CONTROL OF PESTE DES PETITS RUMINANTS IN SMALL RUMINANTS

被引：0
|
作者：
Asim, M. [1 ]
Rashid, A. [1 ]
Chaudhary, A. H. [1 ]
Noor, M. S. [1 ]
机构：
[1] Vet Res Inst, Lahore Cantt, Pakistan
来源：
PAKISTAN VETERINARY JOURNAL | 2009年 / 29卷 / 02期
关键词：
Peste des Petits Ruminants; cell culture; vaccine; live attenuated;
D O I：
暂无
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
Antibody response of a live-attenuated Peste des Petits Ruminants (PPR) cell culture vaccine was studied at Veterinary Research Institute, Lahore, Pakistan. For this purpose, one group of five sheep and 5 goats each was vaccinated subcutaneously with 1 ml reconstituted PPR vaccine and second group of five sheep and 5 goats was inoculated with 1 ml saline solution. Blood samples were collected before and after vaccination, sera were obtained and analyzed for antibodies against PPR by competitive ELISA (cELISA). Findings suggested that antibody titres at day zero, 21 and 45 were 24.762 +/- 2.69, 65.467 +/- 2.29 and 83.012 +/- 2.11 in sheep and 18.723 +/- 2.27, 59.162 +/- 1.53 and 72.176 +/- 2.93 in goats, respectively. No untoward reactions were observed following vaccination. All vaccinated animals developed high titre of antibodies (PI>50).
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页码：72 / 74
页数：3
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