Bariatric surgery as a treatment for idiopathic intracranial hypertension: a systematic review

Background: Idiopathic intracranial hypertension (IIH) is a chronic neurologic disease that may result in persistent and debilitating symptoms that are refractory to conventional treatments. Objectives: The aim of this study was to systematically review the effect of bariatric weight reduction surgery as a treatment for EH. Methods: A comprehensive literature search was conducted using the following databases: MEDLINE, EMBASE, PubMed, Scopus, Web of Sciences, and the Cochrane Library. No restrictions were placed on these searches, including the date of publication. Results: A total of 85 publications were identified, and after initial appraisal, 17 were included in the final review. Overall improvement in symptoms of HET after bariatric surgery was observed in 60 of the 65 patients observed (92%). Postoperative lumbar puncture opening pressure was shown to decrease by an average of 18.9 cm H2O in the 12 patients who had this recorded. Conclusion: Bariatric surgery for weight loss is associated with alleviation of BB symptoms and a reduction in intracranial pressure. Furthermore, an improvement was observed in patients where conventional treatments, including neurosurgery, were ineffective. Further prospective randomized studies with control groups and a larger number of participants are lacking within the published studies to date. There is, therefore, a strong rationale for the use of bariatric surgery in individuals with RH for the effective treatment of this condition, as well as the efficacy of weight loss for various other obesity co-morbidities. (C) 2015 American Society for Metabolic and Bariatric Surgery. All rights reserved.