Quality of life following extratemporal epilepsy surgery

Extratemporal epileptic foci are increasingly treated successfully with surgery. This study assesses the effect of extratemporal epilepsy surgery on the subjective handicaps of epilepsy patients. Twenty-one adults with pharmacoresistant focal epilepsy undergoing extratemporal surgical interventions were analyzed compared to an age-, gender-, and IQ-matched patient group with temporal lobe epilepsy. A questionnaire on subjective handicaps was given prior to surgery and after 1 year of follow-up. There were significant postoperative improvements in the domains of work and activities, self perception, and judgement of changes in handicap. These changes were similar to those in patients undergoing temporal lobe surgery and not restricted to those achieving complete seizure remission. Epilepsy surgery thus improves not only seizure control but also quality of life in patients with extratemporal focus localization.