Prognostic value of the neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and systemic immune-inflammation index in patients with laryngeal squamous cell carcinoma

被引：18
|
作者：
Li, Zhilin [1 ,2 ,3 ]
Qu, Yi [1 ]
Yang, Yang [1 ]
An, Wei [1 ]
Li, Shaoqing [1 ]
Wang, Bin [1 ]
He, Ying [1 ]
Li, Jing [1 ]
Shao, Qi [1 ]
Qin, Lizheng [1 ]
机构：
[1] Capital Med Univ, Beijing Stomatol Hosp, Dept Oral & Maxillofacial & Head & Neck Oncol, 4 Tian Tan Xi Li, Beijing 100050, Peoples R China
[2] Shanxi Med Univ, Shanxi Prov Canc Hosp, Dept Head & Neck Oncol, Taiyuan, Peoples R China
[3] Shanxi Med Univ, Affiliated Canc Hosp, Taiyuan, Peoples R China
来源：
CLINICAL OTOLARYNGOLOGY | 2021年 / 46卷 / 02期
关键词：
laryngeal squamous cell carcinoma; neutrophil‐ to‐ lymphocyte ratio; platelet‐ prognosis; systemic immune‐ inflammation index; LUNG-CANCER; SURVIVAL; HEAD; PLR; NLR;
D O I：
10.1111/coa.13689
中图分类号：
R76 [耳鼻咽喉科学];
学科分类号：
100213 ;
摘要：
Objectives We aimed to determine the prognostic value of the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and systemic immune-inflammation index (SII) in patients with laryngeal squamous cell carcinoma (LSCC). Design and setting A retrospective analysis of patients with LSCC was conducted in our hospitals. Clinical information, including age, sex, TNM classification and other demographic and clinical data, was acquired and analysed. Progression-free survival (PFS) and overall survival (OS) were calculated and compared using the Kaplan-Meier method and log-rank test. Participants A total of 147 patients with LSCC were included. Results According to the receiver operating characteristic (ROC) curve, the optimal cut-off points for NLR, PLR and SII were 1.88, 117.36 and 517.64. The analysis revealed NLR, PLR and SII to be independent predictors for OS and PFS (P < .05). Conclusions Preoperative NLR, PLR and SII are promising prognostic predictors for patients with LSCC.
引用
收藏
页码：395 / 405
页数：11
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