Chronic pulmonary mucormycosis: an emerging fungal infection in diabetes mellitus

被引:16
|
作者
Iqbal, Nousheen [1 ]
Irfan, Muhammad [1 ]
Jabeen, Kauser [2 ]
Kazmi, Murtaza Mohammed [1 ]
Tariq, Muhammad Usman [3 ]
机构
[1] Aga Khan Univ, Dept Med, Sect Pulmonol & Crit Care, Stadium Rd, Karachi, Pakistan
[2] Aga Khan Univ, Dept Pathol & Lab Med, Karachi, Pakistan
[3] Aga Khan Univ Hosp, Sect Histopathol, Dept Pathol & Microbiol, Karachi, Pakistan
关键词
Diabetes; pulmonary mucormycosis (PM); immunocompromised; MANAGEMENT; DIAGNOSIS; PATIENT;
D O I
10.21037/jtd.2017.02.31
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Mucormycosis commonly affects immunocompromised individuals with defects in neutrophil function or count. Diabetes mellitus is an important risk factor due to impair innate and acquired immunity for mucormycosis, with rhino-orbital-cerebral involvement as a common presentation. Pulmonary mucormycosis (PM) although a rare presentation in diabetic patients but is associated with high mortality and morbidity. An early diagnosis of PM is difficult, due to rarity of the disease and clinical and radiological features resembling tuberculosis (TB) which is common in Pakistan. Here we present three cases of chronic PM in patients with diabetes and with no other apparent risk factors.
引用
收藏
页码:E121 / E125
页数:5
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