Hematopoietic stem cell biology: too much of a Wnt thing

被引:26
|
作者
Trowbridge, Jennifer J. [1 ]
Moon, Randall T.
Bhatia, Mickie
机构
[1] McMaster Stem Cell & Canc Res Inst, Hamilton, ON L9G 4L6, Canada
[2] McMaster Univ, Dept Biochem, Hamilton, ON, Canada
[3] Univ Washington, Sch Med, Howard Hughes Med Inst, Dept Pharmacol, Seattle, WA 98195 USA
[4] Univ Washington, Sch Med, Inst Stem Cell & Regenerat Med, Seattle, WA 98195 USA
关键词
D O I
10.1038/ni1006-1021
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Wnt signaling has been shown to be involved in stem cell regulation and may represent a key pathway in controlling hematopoiesis. But is it possible for hematopoietic stem cells to get too much of a good thing?.
引用
收藏
页码:1021 / 1023
页数:4
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