Making a case "for" focal therapy of the prostate in intermediate risk prostate cancer: current perspective and ongoing trials

被引：10
|
作者：
Wang, Alex Z. [1 ]
Lebastchi, Amir H. [1 ,9 ]
O'Connor, Luke P. [1 ]
Ahdoot, Michael [1 ]
Mehralivand, Sherif [2 ]
Yerram, Nitin [1 ]
Taneja, Samir S. [3 ]
George, Arvin K. [4 ]
Sanchez-Salas, Rafael [5 ,6 ]
Ward, John F. [7 ]
Laguna, Pilar [8 ]
de la Rosette, Jean [8 ]
Pinto, Peter A. [1 ]
机构：
[1] NCI, Urol Oncol Branch, NIH, Bethesda, MD 20892 USA
[2] NCI, Mol Imaging Branch, NIH, Bethesda, MD 20892 USA
[3] NYU, Sch Med, Dept Urol, Div Urol Oncol,NYU Langone Hlth, New York, NY 10003 USA
[4] Michigan Med, Dept Urol, Ann Arbor, MI USA
[5] Inst Mutualiste Montsouris, Dept Urol, Paris, France
[6] Univ Paris 05, Paris, France
[7] Univ Texas MD Anderson Canc Ctr, Dept Urol, Houston, TX 77030 USA
[8] Istanbul Medipol Univ, Dept Urol, Istanbul, Turkey
[9] 10 Ctr Dr,Bldg 10,Room 1-5950, Bethesda, MD 20892 USA
来源：
WORLD JOURNAL OF UROLOGY | 2021年 / 39卷 / 03期
关键词：
Focal therapy; prostate cancer; MRI; WHOLE-GLAND CRYOTHERAPY; RADICAL PROSTATECTOMY; LASER-ABLATION; ACTIVE SURVEILLANCE; UNITED-STATES; INDEX LESION; FOLLOW-UP; OUTCOMES; MORTALITY; RADIATION;
D O I：
10.1007/s00345-020-03525-0
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Focal therapy is growing as an alternative management options for men with clinically localized prostate cancer. Parallel to the increasing popularity of active surveillance (AS) as a treatment for low-risk disease, there has been an increased interest towards providing focal therapy for patients with intermediate-risk disease. Focal therapy can act as a logical "middle ground" in patients who seek treatment while minimizing potential side effects of definitive whole-gland treatment. The aim of the current review is to define the rationale of focal therapy in patients with intermediate-risk prostate cancer and highlight the importance of patient selection in focal therapy candidacy.
引用
收藏
页码：729 / 739
页数：11
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