Total synthesis of (-)-amphidinolide P

被引：78
|
作者：
Williams, DR [1 ]
Myers, BJ [1 ]
Mi, L [1 ]
机构：
[1] Indiana Univ, Dept Chem, Bloomington, IN 47405 USA
来源：
ORGANIC LETTERS | 2000年 / 2卷 / 07期
关键词：
D O I：
10.1021/ol0000197
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
[GRAPHICS] The convergent enantiocontrolled total synthesis of the 15-membered macrolactone (-)-amphidinolide P is reported. Key transformations include a Sakurai allylation, a Stille coupling for the formation of a fully functionalized acyclic precursor, and intramolecular transesterification.
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页码：945 / 948
页数：4
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