Standard Treatment Recommendations for Advanced Gastroenteropancreatic Neuroendocrine Carcinomas (GEP-NECs)

Gastroenteropancreatic Neuroendocrine Carcinomas (GEP-NETs), also known as carcinoids and islet cell tumours, are tumours produced from neuroendocrine cells that can arise anywhere along the gastrointestinal system. They are a diverse family of neoplasms with a broad and complex clinical range. Neuroendocrine tumours are tumours that arise in neuroendocrine cells, which are specialized cells. Neuroendocrine cells share characteristics with nerve cells and hormone-producing cells. Neuroendocrine tumours are uncommon and can develop anywhere in the body. Endocrinol cells found in the gastroenteric mucosa as well as those found in the pancreas, mostly comprising islets of Langerhans, are referred to as Gastroenteropancreatic (GEP) endocrine cells.