Synthesis and Antimicrobial Activity of Mono, Bis and Tris 2-Amino-4H-Chromenes

被引：13

作者：

Nikpassand, Mohammad ^{[1
]}

Fekri, Leila Zare ^{[2
]}

Badri, Hanieh ^{[1
]}

Asadpour, Leila ^{[3
]}

机构：

[1] Islamic Azad Univ, Dept Chem, Rasht Branch, Rasht, Iran

[2] Payame Noor Univ, Dept Chem, Tehran, Iran

[3] Islamic Azad Univ, Dept Vet, Rasht Branch, Rasht, Iran

来源：

LETTERS IN ORGANIC CHEMISTRY | 2015年 / 12卷 / 10期

关键词：

Antimicrobial; chromenes; ionic liquid; multicomponent reaction; alpha-Naphthol; malononitrile; ONE-POT; NEW-GENERATION; CATALYST; ACID; CHEMISTRY; COUMARINS; ANALOGS; FACILE; GREEN;

D O I：

10.2174/157017861210151102151656

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A clean and environmentally benign route to 2-amino-4H-chromenes has been developed using the reaction between various benzaldehydes, malononitrile and alpha-naphthol in the presence of 3,3'-(pentane-1,5-diyl) bis(1,2-dimethyl-1H-imidazol-3-ium) bromide. The present methodology offers several advantages such as solvent-free conditions, excellent yields, simple procedure, mild conditions and reduced environmental consequences. The ionic liquid was recovered and reused. All of synthesized compounds were characterized by IR, NMR and Elemental analyses.

引用

页码：685 / 692

页数：8

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