Calcinosis circumscripta in a dog

In the case, calcinosis circumscripta are described with macroscopical and microscopical findings on proximal of right limb in a 2.5 years old, male Rotweiller dog. Macroscopically, all masses were covered with skin and had firm. The cut sections were seen lobullary and composed of well defined areas and vicious and white fluid. Microscopically, it was detected that numbered of restricted areas, where the center had calcification in dark blue stained as haematoxylin eosin (HE) and red stained with Alizerine red S., connective tissue and mononuclear cell infiltration consisting of macrophages, lymphocytes and plasma cells and giant cells.