Fuzzy Sarcomeric Z-disk Complex: α-Actinin-FATZ

被引:0
|
作者
Djinovic-Carugo, Kristina [1 ]
Sponga, Antonio [1 ]
Chamorro, Ariadna Rodriguez [1 ]
de Ribeiro, Euripedes [1 ]
Mlynek, Georg [1 ]
Geist, Leo [1 ]
Arolas, Joan Lopez [1 ]
Konrat, Robert [1 ]
机构
[1] Univ Vienna, Dept Struct & Computat Biol, Max F Perutz Labs, Vienna, Austria
关键词
Striated muscle -Z-disk; actin based cytoskeleton; alpha-actinin; FATZ complex; intrinsically unstructured protein;
D O I
10.1107/S2053273316099551
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
MS6-O1
引用
收藏
页码:S27 / S28
页数:2
相关论文
共 50 条
  • [1] STRUCTURE OF A- ACTININ-2/FATZ-1 FUZZY COMPLEX AND IMPLICATIONS IN Z-DISK FORMATION VIA PHASE SEPARATION
    Sponga, Antonio
    Arolas, Lopez Joan
    Rodriguez-Chamorro, Ariadna
    Ribeiro, De Almeida Euripedes
    Geist, Leonhard
    Drepper, Friedel
    Peterbauer, Thomas
    Mlynek, Georg
    Warscheid, Bettina
    Konrat, Robert
    Djinovic-Carugo, Kristina
    ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 2019, 75 : E143 - E143
  • [2] Sarcomeric Protein Fatz Forms a Tight Fuzzy Complex with α-Actinin and Phase-Separates in Vitro
    Sponga, Antonio
    Arolas, Joan L.
    Schwarz, Thomas C.
    Jeffries, Cy M.
    Kostan, Julius
    Polyansky, Anton A.
    Zagrovic, Bojan
    Svergun, Dmitri
    Warscheid, Bettina
    Konrat, Robert
    Gautel, Mathias
    Djinovic-Carugo, Kristina
    BIOPHYSICAL JOURNAL, 2021, 120 (03) : 61A - 62A
  • [3] Molecular structure of the sarcomeric Z-disk:: two types of titin interactions lead to an asymmetrical sorting of α-actinin
    Young, P
    Ferguson, C
    Bañuelos, S
    Gautel, M
    EMBO JOURNAL, 1998, 17 (06): : 1614 - 1624
  • [4] Binding of α-actinin to titin:: Implications for Z-disk assembly
    Atkinson, RA
    Joseph, C
    Dal Piaz, F
    Birolo, L
    Stier, G
    Pucci, P
    Pastore, A
    BIOCHEMISTRY, 2000, 39 (18) : 5255 - 5264
  • [5] Palindromic assembly of the giant muscle protein titin in the sarcomeric Z-disk
    Zou, PJ
    Pinotsis, N
    Lange, S
    Song, YH
    Popov, A
    Mavridis, I
    Mayans, OM
    Gautel, M
    Wilmanns, M
    NATURE, 2006, 439 (7073) : 229 - 233
  • [6] Palindromic assembly of the giant muscle protein titin in the sarcomeric Z-disk
    Peijian Zou
    Nikos Pinotsis
    Stephan Lange
    Young-Hwa Song
    Alexander Popov
    Irene Mavridis
    Olga M. Mayans
    Mathias Gautel
    Matthias Wilmanns
    Nature, 2006, 439 : 229 - 233
  • [7] Structure of muscle α-actinin: Insights into its regulation and Z-disk assembly
    Ribeiro, E.
    Pinotsis, N.
    Ghisleni, A.
    Salmazo, A.
    Konarev, P.
    Kostan, J.
    Gkougkoulia, E.
    Aachmann, F.
    Pirker, K.
    Svergun, D.
    Gautel, M.
    Djinovic-Carugo, K.
    ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 2014, 70 : C431 - C431
  • [8] STRUCTURAL BASIS OF A-ACTININ-2/TITIN INTERACTION IN THE Z-DISK
    Arolas, Lopez Joan
    Sponga, Antonio
    Smith, Luke
    Gautel, Mathias
    Djinovic-Carugo, Kristina
    ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 2019, 75 : E142 - E142
  • [9] STUDIES OF THE ALPHA-ACTININ ACTIN INTERACTION IN THE Z-DISK BY USING CALPAIN
    GOLL, DE
    DAYTON, WR
    SINGH, I
    ROBSON, RM
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1991, 266 (13) : 8501 - 8510
  • [10] The Z-Disk Diseases
    Selcen, Duygu
    Carpen, Olli
    SARCOMERE AND SKELETAL MUSCLE DISEASE, 2008, 642 : 116 - 130