The Swedish Twin Registry: a unique resource for clinical, epidemiological and genetic studies

被引:542
|
作者
Lichtenstein, P
De Faire, U
Floderus, B
Svartengren, M
Svedberg, P
Pedersen, NL
机构
[1] Karolinska Inst, Dept Med Epidemiol, SE-17177 Stockholm, Sweden
[2] Karolinska Inst, Inst Environm Med, Div Cardiovasc Epidemiol, SE-17177 Stockholm, Sweden
[3] Karolinska Hosp, Dept Cardiol, S-10401 Stockholm, Sweden
[4] Karolinska Inst, Div Environm Med, Inst Environm Med, SE-17177 Stockholm, Sweden
[5] Karolinska Inst, Dept Publ Hlth Sci, SE-17177 Stockholm, Sweden
[6] Natl Inst Working Life, Stockholm, Sweden
[7] Univ So Calif, Dept Psychol, Los Angeles, CA 90089 USA
关键词
D O I
10.1046/j.1365-2796.2002.01032.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The Swedish Twin Registry (STR). which today has developed into a unique resource, was first established in the late 1950s to study the importance of smoking and alcohol consumption on cancer and cardiovascular diseases whilst controlling for genetic propensity to disease. Since that time, the Registry has been expanded and updated on several occasions. and the focus has similarly broadened to most common complex diseases. In the following, we will summarize the content of the database, describe for the first time recent data collection efforts and review some of the principal findings that have come from the Registry.
引用
收藏
页码:184 / 205
页数:22
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