Outbreak of Haff Disease along the Yangtze River Anhui Province, China, 2016

被引:6
|
作者
Ma, Huilai [1 ]
Wu, Jiabing [2 ]
Qin, Wei [1 ,3 ]
Lin, Chao [1 ,4 ]
Li, Dan [1 ]
Zha, Bing [5 ]
Chen, Qi [1 ]
Ma, Yan [1 ]
Zhou, Tichao [1 ]
Li, Shicong [1 ]
Gong, Lei [2 ]
Ma, Wanwan [2 ]
Ge, Dafang [5 ]
Cheng, Zhouxiang [4 ]
Chen, Jian [5 ]
Li, Qun [1 ]
机构
[1] Chinese Ctr Dis Control & Prevent, Beijing, Peoples R China
[2] Anhui Ctr Dis Control & Prevent, Hefei, Peoples R China
[3] Luan Ctr Dis Control & Prevent, Luan, Peoples R China
[4] Wuhu Ctr Dis Control & Prevent, Wuhu, Peoples R China
[5] Maanshan Ctr Dis Control & Prevent, Maanshan, Peoples R China
关键词
RHABDOMYOLYSIS; CONSUMPTION; CRAYFISH;
D O I
10.3201/eid2612.191186
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We investigated a large outbreak of Haff disease that occurred along the Yangtze River in Anhui Province, China, in 2016. Of the 672 cases identified during the outbreak, 83.3% (560/672) occurred in Wuhu and Maanshan. Patients experienced myalgia (100%) and muscle weakness (54.7%). The mean value of myoglobin was 330 + 121.2 ng/mL and of serum creatine kinase 5,439.2 + 4,765.1 U/L. Eating crayfish was the only common exposure among all cases; 96.8% (240/248) of implicated crayfish were caught on the shores of the Yangtze River or its connected ditches. Mean incubation period was 6.2 + 3.8 hours. This casecontrol study demonstrated that eating the liver of crayfish and eating a large quantity of crayfish were associated with an increased risk for Haff disease. The seasonal increases in crayfish population along the Yangtze River might explain the seasonal outbreaks of Haff disease.
引用
收藏
页码:2916 / 2921
页数:6
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