Population Pharmacokinetics of Inotuzumab Ozogamicin (InO) As Single Agent in Pediatric Relapsed/Refractory Acute Lymphoblastic Leukemia - Results from the ITCC-059 Phase IA and Phase II Trial

被引：2

作者：

Pennesi, Edoardo ^{[1
,2
]}

Brivio, Erica ^{[1
,2
]}

Pelletier, Kathleen B. ^{[3
]}

Chen, Ying ^{[4
]}

Huitema, Alwin D. R. ^{[2
,5
,6
]}

Jiang, Yilin ^{[2
]}

Ammerlaan, Anneke C. J. ^{[1
,2
]}

Sleight, Barbara ^{[3
]}

Locatelli, Franco ^{[7
]}

Van der Sluis, Inge M. ^{[2
]}

Rossig, Claudia ^{[8
]}

Chen-Santel, Christiane ^{[9
]}

Bielorai, Bella ^{[10
]}

Petit, Arnaud ^{[11
]}

Stary, Jan ^{[12
]}

Sramkova, Lucie ^{[12
]}

de Heredia Rubio, Cristina Diaz ^{[13
]}

Rives, Susana ^{[14
]}

O'Marcaigh, Aengus ^{[15
]}

Rizzari, Carmelo ^{[16
]}

Engstler, Gernot ^{[17
]}

Nysom, Karsten ^{[18
]}

Rubio-San-Simon, Alba ^{[19
]}

Sirvent, Francisco J. Bautista ^{[2
]}

Bruno, Benedicte ^{[20
]}

Bertrand, Yives ^{[21
]}

Brethon, Benoit ^{[22
]}

Rialland, Fanny ^{[23
]}

Plat, Genevieve ^{[24
]}

Dirksen, Uta ^{[25
]}

Garrett, May ^{[26
]}

Zwaan, Christian M. ^{[1
,2
]}

机构：

[1] Erasmus MC Sophia Childrens Hosp, Dept Pediat Oncol, Rotterdam, Netherlands

[2] Princess Maxima Ctr Pediat Oncol, Utrecht, Netherlands

[3] Pfizer Inc, Groton, CT 06340 USA

[4] Pfizer Inc, La Jolla, CA USA

[5] Univ Med Ctr Utrecht, Utrecht, Netherlands

[6] Netherlands Canc Inst, Amsterdam, Netherlands

[7] Univ Cattolica Sacro Cuore, IRCCS Osped Pediat Bambino Gesu, Rome, Italy

[8] Univ Childrens Hosp Munster, Dept Pediat Hematol & Oncol, Munster, Germany

[9] Rostock Med Ctr, Rostock, Germany

[10] Sheba Med Ctr, Div Pediat Hematol & Oncol, Ramat Gan, Israel

[11] Sorbonne Univ, Trousseau Hosp, Hop Armand Trousseau, AP HP,Pediat Hematol & Oncol Dept, Paris, France

[12] Univ Hosp Motol, Dept Pediat Hematol & Oncol, Prague, Czech Republic

[13] Hosp Univ Vall dHebron, Div Pediat Hematol & Oncol, Barcelona, Spain

[14] Hosp St Joan Deu Barcelona, Dept Pediat Hematol & Oncol, Barcelona, Spain

[15] Hosp Sick Children, Dublin, Ireland

[16] Univ Milano Bicocca, San Gerardo Hosp, MBBM Fdn, Pediat Hematol Oncol Unit, Monza, Italy

[17] Med Univ Vienna, St Anna Childrens Hosp, Vienna, Austria

[18] Rigshosp, Dept Paediat & Adolescent Med, Copenhagen, Denmark

[19] Hosp Nino Jesus, Dept Pediat Oncol & Hematol, Madrid, Spain

[20] CHRU Lille, Hop Jeanne de Flandre, Pediat Hematol, Lille, France

[21] Claude Bernard Univ, Inst Pediat Hematol & Oncol, Civil Hosp Lyon, Lyon, France

[22] Univ Paris, Robert Debre Hosp, AP HP, Dept Pediat Hematol & Immunol, Paris, France

[23] Nantes Univ Hosp, Serv Oncohematol Pediat, Hop Mere Enfant, Nantes, France

[24] CHU Toulouse, Hop Enfants, Serv Hematol Immunol Oncol, Toulouse, France

[25] Essen Univ Hosp, West German Canc Ctr, German Canc Consortium DKTK, Pediat 3, Essen, Germany

[26] Pfizer Oncol, La Jolla, CA USA

来源：

BLOOD | 2022年 / 140卷

关键词：

D O I：

10.1182/blood-2022-165954

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

605

引用

页码：8845 / 8847

页数：3

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