Controllability of depth dose distribution for neutron capture therapy at the heavy Water Neutron Irradiation Facility of Kyoto University Research Reactor

被引:11
|
作者
Sakurai, Y [1 ]
Kobayashi, T [1 ]
机构
[1] Kyoto Univ, Inst Res Reactor, Kumatori, Osaka 5900494, Japan
关键词
neutron capture therapy; dose distribution control; variable neutron energy spectra; neutron spectrum shifter; thermal neutron filter;
D O I
10.1118/1.1509445
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
The updating construction of the Heavy Water Neutron Irradiation Facility of the Kyoto University Research Reactor has been performed from November 1995 to March 1996 mainly for the improvement in neutron capture therapy. On the performance, the neutron irradiation modes with the variable energy spectra from almost pure thermal to epi-thermal neutrons became available by the control of the heavy-water thickness in the spectrum shifter and by the open-and-close of the cadmium and boral thermal neutron filters. The depth distributions of thermal, epi-thermal and fast neutron fluxes were measured by activation method using gold and indium, and the depth distributions of gamma-ray absorbed dose rate were measured using thermo-luminescent dosimeter of beryllium oxide for the several irradiation modes. From these measured data, the controllability of the depth dose distribution using the spectrum shifter and the thermal neutron filters was confirmed. (C) 2002 American Association of Physicists in Medicine.
引用
收藏
页码:2338 / 2350
页数:13
相关论文
共 50 条
  • [1] The medical-irradiation characteristics for neutron capture therapy at the Heavy Water Neutron Irradiation Facility of Kyoto University Research Reactor
    Sakurai, Y
    Kobayashi, T
    MEDICAL PHYSICS, 2002, 29 (10) : 2328 - 2337
  • [2] The remodeling and basic characteristics of the Heavy Water Neutron Irradiation Facility of the Kyoto University Research Reactor, mainly for neutron capture therapy
    Kobayashi, T
    Sakurai, Y
    Kanda, K
    Fujita, Y
    Ono, K
    NUCLEAR TECHNOLOGY, 2000, 131 (03) : 354 - 378
  • [3] The upgrade of the heavy water facility of the Kyoto University Reactor for neutron capture therapy
    Kobayashi, T
    Kanda, K
    Fujita, Y
    Sakurai, Y
    Ono, K
    ADVANCES IN NEUTRON CAPTURE THERAPY, VOLS I AND II: VOL I: MEDICINE AND PHYSICS, VOL II: CHEMISTRY AND BIOLOGY, 1997, 1132 : A321 - A325
  • [4] Characterization of a thermal neutron field at the heavy water neutron irradiation facility of the Kyoto University Reactor
    Uritani, A
    Pyeon, CH
    Kudo, Y
    Kobayashi, K
    Yoshimoto, T
    Sakurai, Y
    Kobayashi, T
    Mori, C
    REACTOR DOSIMETRY IN THE 21ST CENTURY, 2003, : 340 - 344
  • [5] Characteristic comparison between two different neutron spectrometers for boron neutron capture therapy irradiation field developed at Heavy Water Neutron Irradiation Facility of Kyoto University Research Reactor
    Prateepkaew, Jakkrit
    Matsubayashi, Nishiki
    Takata, Takushi
    Tanaka, Hiroki
    Sakurai, Yoshinori
    APPLIED RADIATION AND ISOTOPES, 2025, 219
  • [7] Reevaluation of neutron energy spectrum in Heavy-Water neutron irradiation facility of Kyoto University research Reactor using multifoil activation method
    Prateepkaew, Jakkrit
    Sakurai, Yoshinori
    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS, 2024, 557
  • [8] Spectrum evaluation at the filter-modified neutron irradiation field for neutron capture therapy in Kyoto University Research Reactor
    Sakurai, Y
    Kobayashi, T
    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2004, 531 (03): : 585 - 595
  • [9] Microdosimetry of neutron field for boron neutron capture therapy at Kyoto University Reactor
    Endo, S
    Onizuka, Y
    Ishikawa, M
    Takada, M
    Sakurai, Y
    Kobayashi, T
    Tanaka, K
    Hoshi, M
    Shizuma, K
    RADIATION PROTECTION DOSIMETRY, 2004, 110 (1-4) : 641 - 644
  • [10] The characteristics of the updated heavy water facility of the Kyoto University Reactor (II) (neutron energy spectra for several irradiation modes)
    Sakurai, Y
    Kobayashi, T
    Kobayashi, K
    FRONTIERS IN NEUTRON CAPTURE THERAPY, VOLS 1 AND 2, 2001, : 345 - 349