MDM2 and MDMX promote p53-independent initiation of circulating tumor cells from triple negative breast cancers

被引：0
|
作者：
Gao, Chong [1 ,2 ]
Xiao, Gu [1 ]
Piersiga, Ale [3 ,4 ]
Gou, Jiangtao [1 ]
Ogunwobi, Olorunseun [1 ,2 ]
Bargonetti, Jill [1 ,2 ]
机构：
[1] CUNY, Hunter Coll, New York, NY 10021 USA
[2] CUNY, Grad Ctr, New York, NY USA
[3] Rockefeller Univ, Weill Cornell Med Coll, 1230 York Ave, New York, NY 10021 USA
[4] Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA
来源：
CANCER RESEARCH | 2018年 / 78卷 / 13期
关键词：
D O I：
10.1158/1538-7445.AM2018-5188
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
5188
引用
收藏
页数：2
相关论文
共 50 条
  • [1] p53-independent functions of MDM2
    Ganguli, G
    Wasylyk, B
    MOLECULAR CANCER RESEARCH, 2003, 1 (14) : 1027 - 1035
  • [2] MDM2 promotes p53-independent breast cancer metastatic phenotypes
    Gao, Chong
    Kundu, Nandini
    Bargonetti, Jill
    CANCER RESEARCH, 2015, 75
  • [3] Benzimidazoles Downregulate Mdm2 and MdmX and Activate p53 in MdmX Overexpressing Tumor Cells
    Mrkvova, Zuzana
    Uldrijan, Stjepan
    Pombinho, Antonio
    Bartunek, Petr
    Slaninova, Iva
    MOLECULES, 2019, 24 (11):
  • [4] Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis
    Jones, SN
    Hancock, AR
    Vogel, H
    Donehower, LA
    Bradley, A
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (26) : 15608 - 15612
  • [5] Mdmx promotes genomic instability independent of p53 and Mdm2
    Carrillo, A. M.
    Bouska, A.
    Arrate, M. P.
    Eischen, C. M.
    ONCOGENE, 2015, 34 (07) : 846 - 856
  • [6] Mdmx promotes genomic instability independent of p53 and Mdm2
    A M Carrillo
    A Bouska
    M P Arrate
    C M Eischen
    Oncogene, 2015, 34 : 846 - 856
  • [7] MDM2/MDMX: Master negative regulators for p53 and RB
    Hu, Linshan
    Zhang, Haibo
    Bergholz, Johann
    Sun, Shengnan
    Xiao, Zhi-Xiong Jim
    MOLECULAR & CELLULAR ONCOLOGY, 2016, 3 (02)
  • [8] p53-independent activities of MDM2 and their relevance to cancer therapy
    Zhang, Z
    Zhang, RW
    CURRENT CANCER DRUG TARGETS, 2005, 5 (01) : 9 - 20
  • [9] CHROMATIN-BOUND MDM2 PLAYS A p53-INDEPENDENT ROLE IN TUMOR METABOLISM
    不详
    CANCER DISCOVERY, 2016, 6 (07) : 693 - 693
  • [10] Estrogen receptor alpha (ERα/ESR1) mediates the p53-independent overexpression of MDM4/MDMX and MDM2 in human breast cancer
    Swetzig, Wendy M.
    Wang, Jianmin
    Das, Gokul M.
    ONCOTARGET, 2016, 7 (13) : 16049 - 16069
12345