The ten genes for breast (and ovarian) cancer susceptibility

被引:17
|
作者
Foulkes, William D. [1 ,2 ,3 ]
机构
[1] McGill Univ, Dept Med, Montreal, PQ, Canada
[2] McGill Univ, Dept Human Genet, Montreal, PQ, Canada
[3] McGill Univ, Dept Oncol, Montreal, PQ, Canada
关键词
D O I
10.1038/s41571-021-00491-3
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
ATM, BRCA1, BRCA2, CHEK2, PALB2 and TP53 are all established breast cancer susceptibility genes. Over the past 30 years, many other genes have been proposed as candidates. In these two large studies, the candidacy of several questionable genes has been largely resolved, and a final list of ten genes for breast and, importantly, ovarian cancer risk has emerged.
引用
收藏
页码:259 / 260
页数:2
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