Specific targeting of inducible nitric oxide synthase (iNOS) gene to CEA-expressing tumor cells by a retroviral vector displaying a single-chain variable fragment (scFv) antibody.

被引：0
|
作者：
Kuroki, M [1 ]
Khare, PD [1 ]
Liao, S [1 ]
Kuroki, M [1 ]
Arakawa, F [1 ]
机构：
[1] Fukuoka Univ, Sch Med, Dept Biochem 1, Fukuoka 8140180, Japan
来源：
CLINICAL CANCER RESEARCH | 1999年 / 5卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
506
引用
收藏
页码：3831S / 3831S
页数：1
相关论文
共 20 条
  • [1] Specifically targeted killing of carcinoembryonic antigen (CEA)-expressing cells by a retroviral vector displaying single-chain variable fragmented antibody to CEA and carrying the gene for inducible nitric oxide synthase
    Khare, PD
    Liao, SX
    Kuroki, M
    Hirose, Y
    Arakawa, F
    Nakamura, K
    Tomita, Y
    Kuroki, M
    CANCER RESEARCH, 2001, 61 (01) : 370 - 375
  • [2] Specific targeting strategies of cancer gene therapy using a single-chain variable fragment (scFv) with a high affinity for CEA
    Kuroki, M
    Arakawa, F
    Khare, PD
    Kuroki, M
    Liao, SX
    Matsumoto, H
    Abe, H
    Imakiire, T
    ANTICANCER RESEARCH, 2000, 20 (6A) : 4067 - 4071
  • [3] Targeting of T cells to CEA-expressing tumor cells by chimeric immune receptors with a highly specific single-chain anti-CEA activity
    Arakawa, F
    Shibaguchi, H
    Xu, ZW
    Kuroki, M
    ANTICANCER RESEARCH, 2002, 22 (6C) : 4285 - 4289
  • [4] Tumor cell-specific gene transfer with retroviral vectors displaying single-chain antibody
    Tang, YC
    Li, Y
    Qian, GX
    CHINESE MEDICAL JOURNAL, 2002, 115 (07) : 1064 - 1069
  • [5] Targeting of c-met and urokinase expressing human glioma cell lines by retrovirus vector displaying single-chain variable fragment antibody
    Solly, SK
    Nguyen, TH
    Weber, A
    Horellou, P
    CANCER BIOLOGY & THERAPY, 2005, 4 (09) : 987 - 992
  • [6] Recombinant bispecific antibodies for the targeting of adenoviruses to CEA-expressing tumour cells:: a comparative analysis of bacterially expressed single-chain diabody and tandem scFv
    Korn, T
    Nettelbeck, DM
    Völkel, T
    Müller, R
    Kontermann, RE
    JOURNAL OF GENE MEDICINE, 2004, 6 (06): : 642 - 651
  • [7] Targeting strategy for gene delivery to carcinoembryonic antigen-producing cancer cells by retrovirus displaying a single-chain variable fragment antibody
    Konishi, H
    Ochiya, T
    Chester, KA
    Begent, RHJ
    Muto, T
    Sugimura, T
    Terada, M
    HUMAN GENE THERAPY, 1998, 9 (02) : 235 - 248
  • [8] Improved gene transfer selectivity to hepatocarcinoma cells by retrovirus vector displaying single-chain variable fragment antibody against c-Met
    Nguyen, TH
    Loux, N
    Dagher, I
    Vons, C
    Carey, K
    Briand, P
    Hadchouel, M
    Franco, D
    Jouanneau, J
    Schwall, R
    Weber, A
    CANCER GENE THERAPY, 2003, 10 (11) : 840 - 849
  • [9] Improved gene transfer selectivity to hepatocarcinoma cells by retrovirus vector displaying single-chain variable fragment antibody against c-Met
    Tuan Huy Nguyen
    Nathalie Loux
    Ibrahim Dagher
    Corinne Vons
    Ken Carey
    Pascale Briand
    Michelle Hadchouel
    Dominique Franco
    Jacqueline Jouanneau
    Ralph Schwall
    Anne Weber
    Cancer Gene Therapy, 2003, 10 : 840 - 849
  • [10] Targeted macrophage cytotoxicity using a nonreplicative live vector expressing a tumor-specific single-chain variable region fragment
    Paul, S
    Snary, D
    Hoebeke, J
    Allen, D
    Balloul, JM
    Bizouarne, N
    Dott, K
    Geist, M
    Hilgers, J
    Kieny, MP
    Burchell, J
    Papadimitriou, JT
    Acres, RB
    HUMAN GENE THERAPY, 2000, 11 (10) : 1417 - 1428
12