A note on multiple testing procedures in dose finding

被引:32
|
作者
Bauer, P
机构
[1] Department of Medical Statistics, University of Vienna, A-1090 Vienna
关键词
dose finding; familywise error rate; multiple tests; order restrictions;
D O I
10.2307/2533569
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
It is shown that, in some recently proposed multiple test procedures for dose finding (Tamhane, Hochberg, and Dunnett, 1996, Biometrics 52, 21-37), strong control of the familywise error is only guaranteed if order relations are assumed to hold among the means. Procedures that can be applied safely without assuming any restrictions on the means can be based on the classical many-one comparisons of doses with the zero dose.
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页码:1125 / 1128
页数:4
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